Cox F M E, Cornel J H, Aramideh M
Medisch Centrum Alkmaar.
Ned Tijdschr Geneeskd. 2006 Jun 17;150(24):1347-50.
A 34-year-old alcoholic man had neurological and cardiac symptoms. The patient was admitted to the hospital for acute painful sensory disturbances and severe weakness of the feet. Neurological and electrophysiological investigation revealed axonal sensorimotor polyneuropathy that was most prominent in the legs. Cardiac assessment showed signs and symptoms of heart failure due to a high-output state. Blood analysis showed a low thiamine concentration of 58 nmol/l (lower reference limit: 80). Therefore, a diagnosis of combined wet beriberi with cardiomyopathy and dry beriberi with axonal polyneuropathy was made. The treatment of beriberi is simple and effective and consists of thiamine supplementation in conjunction with diuretic treatment. With this approach, the patient recovered fully. Patients with beriberi have a good prognosis, particularly when the diagnosis is made at an early stage.
一名34岁的酗酒男子出现了神经和心脏症状。该患者因急性疼痛性感觉障碍和足部严重无力入院。神经学和电生理检查显示轴索性感觉运动性多发性神经病，在腿部最为明显。心脏评估显示因高输出状态导致心力衰竭的体征和症状。血液分析显示硫胺素浓度低至58 nmol/l（参考下限：80）。因此，诊断为湿性脚气病合并心肌病以及干性脚气病合并轴索性多发性神经病。脚气病的治疗简单有效，包括补充硫胺素并结合利尿剂治疗。采用这种方法，患者完全康复。脚气病患者预后良好，尤其是在早期诊断时。
