Paraneoplastic cerebellar degeneration with anti-Yo antibody in a man.

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作者信息

Felician O, Renard J L, Vega F, Créange A, Chen Q M, Bequet D, Delattre J Y

机构信息

Clinique de Neurologie et de Neuropsychologie, Hôpital du Val de Grâce, Paris, France.

出版信息

Neurology. 1995 Jun;45(6):1226-7. doi: 10.1212/wnl.45.6.1226.

DOI:10.1212/wnl.45.6.1226

PMID:7783900

Abstract

摘要

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Paraneoplastic cerebellar degeneration with anti-Yo antibody in a man.

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Cytotoxic T cells react with recombinant Yo protein from a patient with paraneoplastic cerebellar degeneration and anti-Yo antibody.细胞毒性T细胞与一名副肿瘤性小脑变性患者的重组Yo蛋白及抗Yo抗体发生反应。

J Neurol Sci. 1998 Nov 26;161(1):88-90. doi: 10.1016/s0022-510x(98)00257-3.

Trial to establish an animal model of paraneoplastic cerebellar degeneration with anti-Yo antibody. 2. Passive transfer of murine mononuclear cells activated with recombinant Yo protein to paraneoplastic cerebellar degeneration lymphocytes in severe combined immunodeficiency mice.建立抗Yo抗体介导的副肿瘤性小脑变性动物模型的试验。2. 将用重组Yo蛋白激活的小鼠单核细胞被动转移至重度联合免疫缺陷小鼠的副肿瘤性小脑变性淋巴细胞中。

Clin Neurol Neurosurg. 1995 Feb;97(1):101-5. doi: 10.1016/0303-8467(95)00006-6.

Paraneoplastic cerebellar degeneration. I. A clinical analysis of 55 anti-Yo antibody-positive patients.副肿瘤性小脑变性。I. 55例抗Yo抗体阳性患者的临床分析。

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Trial to establish an animal model of paraneoplastic cerebellar degeneration with anti-Yo antibody. 1. Mouse strains bearing different MHC molecules produce antibodies on immunization with recombinant Yo protein, but do not cause Purkinje cell loss.建立抗Yo抗体介导的副肿瘤性小脑变性动物模型的实验。1. 携带不同主要组织相容性复合体（MHC）分子的小鼠品系在用重组Yo蛋白免疫后会产生抗体，但不会导致浦肯野细胞丢失。

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Association of anti-Yo (type I) antibody with paraneoplastic cerebellar degeneration in the setting of transitional cell carcinoma of the bladder: detection of Yo antigen in tumor tissue and fall in antibody titers following tumor removal.抗Yo（I型）抗体与膀胱移行细胞癌背景下的副肿瘤性小脑变性的关联：肿瘤组织中Yo抗原的检测及肿瘤切除后抗体滴度的下降

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A review of the therapy of paraneoplastic neurologic syndromes.副肿瘤性神经系统综合征的治疗综述。

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