Richardson J
Department of Anaesthetics, Bradford Royal Infirmary, UK.
Postgrad Med J. 1995 Apr;71(834):242-4. doi: 10.1136/pgmj.71.834.242.
A 54-year-old man who had an appearance strongly suggestive of Cushing's syndrome, collapsed after the removal of a carcinoid tumour of the thymus. The clinical suspicion of acute adrenal insufficiency was supported by invasive haemodynamic data and the diagnosis was subsequently confirmed biochemically. These post-operative events were subsequently ignored and a further crisis was probably prevented by tumour recurrence (and hence resumption of adrenocorticotropic hormone (ACTH) production). The ectopic production of ACTH from a carcinoid tumour of the thymus is recognised but a report of acute adrenal insufficiency from its removal is probably unique.
一名54岁男性,其外貌强烈提示库欣综合征,在切除胸腺类癌肿瘤后出现虚脱。侵入性血流动力学数据支持临床对急性肾上腺功能不全的怀疑,随后通过生化检查确诊。这些术后事件随后被忽视,肿瘤复发(从而恢复促肾上腺皮质激素(ACTH)分泌)可能避免了进一步的危机。胸腺类癌肿瘤异位分泌ACTH已得到公认,但因切除该肿瘤导致急性肾上腺功能不全的报道可能是独一无二的。