Shust V F
Vestn Rentgenol Radiol. 1994 Jul-Aug(4):18-21.
Subtotal irradiation after a method developed at the Central Research Roentgeno-Radiological Institute in St.-Petersburg was used as the first stage of antitumor treatment in 15 patients with Hodgkin's disease. In another group of 15 patients with the same disease antitumor treatment was started with a cycle of polychemotherapy. Comparison of the two types of total-system cytostatic therapy demonstrated their similar antitumor efficacy as far as the immediate results were concerned, but it also showed a higher hematologic toxicity of subtotal irradiation vs. polychemotheapy. Possibility of assessing the total dose of cytostatic exposure in multiple-modality treatment (chemoradiotherapy) is discussed.
采用圣彼得堡中央研究伦琴放射学研究所研发的一种方法进行的局部照射，被用作15例霍奇金病患者抗肿瘤治疗的第一阶段。在另一组15例患有相同疾病的患者中，抗肿瘤治疗从多药化疗周期开始。对两种类型的全身细胞抑制疗法的比较表明，就近期结果而言，它们的抗肿瘤疗效相似，但也显示出局部照射相对于多药化疗具有更高的血液学毒性。文中讨论了在多模式治疗（放化疗）中评估细胞抑制暴露总剂量的可能性。
