Rühl D, Werner K, Poustka F
Klinikum der Johann Wolfgang Goethe-Universität, Zentrum Psychiatrie, Abteilung für Kinder- und Jugendpsychiatrie.
Z Kinder Jugendpsychiatr. 1995 Jun;23(2):95-103.
In a research project on the genetics of autistic disorders 115 subjects were examined. An autistic disorder was diagnosed in 102 of the subjects using the standardized Autism Diagnostic Interview (ADI; Le Couteur et al., 1989/ADI-R; Lord et al., 1994). The WAIS-R or WISC-R could be administered to 42 of the subjects. The mean full-scale IQ was 84.4, slightly below the range of normal intelligence. The mean verbal IQ (89.3) was considerably higher than the performance IQ (78.9). Analysis of the subtest patterns showed the highest scores to be in those subtests measuring knowledge of dates and facts and visuospatial abilities. The lowest scores were on subtests requiring an understanding of social relations and the ability to understand concrete social actions. This subtest pattern confirms results of other studies on the intelligence of individuals with autism and was independent of gender and level of intelligence. The subtest pattern appears to be specific for autistic disorder; it has been interpreted with reference to the theory of "weak central coherence" (Frith, 1989; Shah & Frith, 1993), which postulates that in autistic individuals stimulus perception and processing occurs independently of the general context. The results suggest that the differentiation between different types of autistic disorders should be abandoned in favor of a continuum of autistic disorders with differing degrees of severity.
在一项关于自闭症谱系障碍遗传学的研究项目中,对115名受试者进行了检查。使用标准化的自闭症诊断访谈(ADI;勒库特尔等人,1989年/ADI-R;洛德等人,1994年)对其中102名受试者诊断出自闭症谱系障碍。42名受试者接受了韦氏成人智力量表修订版(WAIS-R)或韦氏儿童智力量表修订版(WISC-R)测试。平均全量表智商为84.4,略低于正常智力范围。平均言语智商(89.3)显著高于操作智商(78.9)。对各分测验模式的分析表明,得分最高的是那些测量日期和事实知识以及视觉空间能力的分测验。得分最低的是那些需要理解社会关系和理解具体社会行为能力的分测验。这种分测验模式证实了其他关于自闭症患者智力研究的结果,且与性别和智力水平无关。这种分测验模式似乎是自闭症谱系障碍所特有的;它已根据“弱中央连贯性”理论(弗里思,1989年;沙阿和弗里思,1993年)进行了解释,该理论假定自闭症患者的刺激感知和处理独立于一般背景进行。结果表明,应放弃对不同类型自闭症谱系障碍的区分,转而支持一个具有不同严重程度的自闭症谱系障碍连续体。