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小鼠卵巢隔室在排卵期及阻断促性腺激素高峰后肥大细胞数量和脱颗粒模式的变化。

Changes in the mast cell number and degranulation pattern during periovulatory period and after blocking gonadotrophin surge in mice ovarian compartments.

作者信息

Krishna A, Jaiswal K

机构信息

Department of Zoology, Banaras Hindu University, Varanasi, India.

出版信息

Acta Physiol Hung. 1994;82(4):415-21.

PMID:7785452
Abstract

Mast cell in the ovary of cyclic mice were observed in the ovarian medulla, hilum and bursa, but not in the cortex. A significant increase in the degranulation of mast cells was observed in the hilum and bursa but not in the medulla following the gonadotrophin (Gn) surge as compared with before the surge at proestrus. The results of pentobarbital treatment at proestrus imply the significant role played by estradiol 17-beta (E2) in inducing mast cells migration and degranulation, specially in the medullary, cortical and bursal region of the ovary. The results indicate differential regulation of mast cells number and degranulation in different ovarian compartments of mice.

摘要

在处于发情周期的小鼠卵巢中,肥大细胞可见于卵巢髓质、门部和囊,但皮质中未见。与发情前期促性腺激素(Gn)激增前相比,Gn激增后观察到门部和囊中的肥大细胞脱颗粒显著增加,但髓质中未见。发情前期戊巴比妥处理的结果表明,17-β-雌二醇(E2)在诱导肥大细胞迁移和脱颗粒中发挥了重要作用,特别是在卵巢的髓质、皮质和囊区。结果表明小鼠不同卵巢区域中肥大细胞数量和脱颗粒存在差异调节。

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