Jaiswal K, Krishna A
Department of Zoology, Banaras Hindu University, Varanasi, India.
Acta Physiol Hung. 1996;84(2):183-90.
The changes in the number and degranulation pattern of mast cells varied with the types of hormonal treatment and ovarian compartment. Luteinizing hormone (LH), follicle stimulating hormone (FSH), thyroid stimulating hormone (TSH) and 17-beta estradiol (E2) treatment caused increase (P < 0.05) in the number of mast cells in the hilum as compared with the controls. Increase (P < 0.05) in the number of mast cells in the whole ovarian complex was observed only following FSH and E2 treatment. All the hormones used in the present study increased the percentage degranulation of mast cells in the hilum. However, only LH, FSH and E2 increased the percentage degranulation of mast cells in other compartments of the ovary (medulla, bursa and cortex). TSH and ACTH failed to cause any increase in the percentage degranulation of mast cells in these compartments. The present findings indicate E2 to be the most potent among the hormones tested in causing degranulation of mast cells in all ovarian compartments.
肥大细胞的数量和脱颗粒模式变化随激素治疗类型和卵巢区域而异。与对照组相比，促黄体生成素（LH）、促卵泡激素（FSH）、促甲状腺激素（TSH）和17-β雌二醇（E2）治疗导致卵巢门区肥大细胞数量增加（P<0.05）。仅在FSH和E2治疗后，观察到整个卵巢复合体中肥大细胞数量增加（P<0.05）。本研究中使用的所有激素均增加了卵巢门区肥大细胞的脱颗粒百分比。然而，只有LH、FSH和E2增加了卵巢其他区域（髓质、囊和皮质）肥大细胞的脱颗粒百分比。TSH和促肾上腺皮质激素（ACTH）未能使这些区域的肥大细胞脱颗粒百分比增加。目前的研究结果表明，在所有测试激素中，E2在引起所有卵巢区域肥大细胞脱颗粒方面最有效。
