Tsuzuki M, Kawakami S, Yonese J, Kageyama S, Yoshimura K, Yamauchi T, Kawai T
Hinyokika Kiyo. 1995 Apr;41(4):301-4.
A 60-year-old man visited our hospital with a chief complaint of penile tumor on November 13, 1984. Circumcision of true phimosis was performed and biopsy of the 27 x 27 mm fixed tumor on the glans revealed well differentiated squamous cell carcinoma. Seventy Gy of electron irradiation to the penis revealed a complete response. On February 1, 1985 bilateral inguinal lymph node dissection was performed and revealed metastasis to a left inguinal node. In May 1990, erosive changes occurred on the irradiated region, and local recurrence was confirmed. Since 2 courses of MBD (methotrexate, bleomycin, cisplatin) chemotherapy was not effective, additional wedge dissection was performed. In January 1992, local recurrence was found. Four courses of intra-arterial chemotherapy (cisplatin, vincristine, methotrexate, adriamycin) was performed with a complete response. No evidence of disease has been recognized for more than two years after completion of the treatment.
1984年11月13日，一名60岁男性因阴茎肿瘤为主诉前来我院就诊。对真性包茎进行了包皮环切术，对龟头处27×27mm的固定肿瘤进行活检，结果显示为高分化鳞状细胞癌。对阴茎进行70Gy的电子照射后显示完全缓解。1985年2月1日进行了双侧腹股沟淋巴结清扫术，发现左侧腹股沟淋巴结转移。1990年5月，照射区域出现糜烂性改变，证实为局部复发。由于两疗程的MBD（甲氨蝶呤、博来霉素、顺铂）化疗无效，遂进行了额外的楔形切除术。1992年1月，发现局部复发。进行了四疗程的动脉内化疗（顺铂、长春新碱、甲氨蝶呤、阿霉素），结果完全缓解。治疗完成后两年多未发现疾病迹象。
