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[肌内注射双氢麦角胺对术后早期血液循环的影响。一项临床研究]

[Effect of intramuscular dihydroergotamine on blood circulation in the early postoperative phase. A clinical study].

作者信息

Martin E, Immich H, Lutz H, Peter K

出版信息

Med Klin. 1976 May 28;71(22):961-5.

PMID:778569
Abstract

The effects of Dihydergot (1,0 mg i.m.) and a placebo on orthostatic regulation disturbances were examined during the mobilisation in the first post-operative phase. According to a modified Schellong-test, 100 fresh-operated patients with hyper- rsp. hypodiastolic regulation disturbances were checked on the first post-operative day. In comparison with the placebo, Dihydergot showed a stabilisation of the systolic blood pressure and a decrease of the pulse rate during orthostatic conditions. Neither Dihydergot nor placebo influenced the diastolic blood pressure. Orthostatically caused side effects were observed less frequent within Dihydergot - therapy than under placebo.

摘要

在术后第一阶段的活动期间,研究了双氢麦角胺(1.0毫克,肌肉注射)和安慰剂对体位调节障碍的影响。根据改良的谢隆试验,在术后第一天对100例刚做完手术且有高反应性或低舒张期调节障碍的患者进行了检查。与安慰剂相比,双氢麦角胺在体位状态下可使收缩压稳定,并使脉搏率降低。双氢麦角胺和安慰剂均未影响舒张压。与安慰剂治疗相比,双氢麦角胺治疗期间观察到的体位性副作用较少。

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