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双氢麦角胺与普萘洛尔对急性直立性低血压的作用(作者译)

[The effect of dihydroegotamine and propanolol on acute orthostasis (author's transl)].

作者信息

Weidinger P, Steinbach K

出版信息

Wien Klin Wochenschr. 1976 Apr 2;88(7):236-8.

PMID:983076
Abstract

10 Patients with positive orthostatic dysregulation were investigated with regard to venous capacity, heart frequency and arterial blood pressure both lying down and sitting up. The venous capacity was reduced by 14% after dehydroergotamine (DHE) in the lying position, which is an expression of increased venous tone. There is no change in venous capacity following the administration of beta blockers in the lying position. Under orthostatic conditions beta blockers bring about an approximate normalization of the venous capacity reaction, whereas the abnormal response following placebo administration is only slightly altered by DHE.

摘要

对10例体位性调节障碍阳性患者在卧位和坐立时的静脉容量、心率和动脉血压进行了研究。在卧位时,使用双氢麦角胺(DHE)后静脉容量减少了14%,这表明静脉张力增加。卧位时使用β受体阻滞剂后静脉容量无变化。在体位性条件下,β受体阻滞剂可使静脉容量反应大致恢复正常,而安慰剂给药后的异常反应仅被DHE轻微改变。

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