婴儿期的强直性瞳孔与眶部神经胶质神经错构瘤

Tonic pupil and orbital glial-neural hamartoma in infancy.

作者信息

Brooks-Kayal A R, Liu G T, Menacker S J, Heher K L, Katowitz J A, Bilaniuk L T

机构信息

Neurology Service, University of Pennsylvania School of Medicine, USA.

出版信息

Am J Ophthalmol. 1995 Jun;119(6):809-11. doi: 10.1016/s0002-9394(14)72796-5.

DOI:10.1016/s0002-9394(14)72796-5

PMID:7785705

Abstract

PURPOSE/METHODS: Tonic pupils in early childhood are rare. We studied an otherwise healthy 31/2-month-old girl who had a right pupil that was poorly reactive to light, without other signs of oculomotor nerve palsy.

RESULTS/CONCLUSIONS: Constriction of the right pupil after instillation of 0.125% pilocarpine eyedrops confirmed denervation hypersensitivity, consistent with a tonic pupil. There was no strabismus or proptosis. A magnetic resonance imaging scan demonstrated a right orbital mass, interposed between the lateral and inferior recti muscles. Biopsy was consistent with a benign, glial-neural hamartoma. Thus, in this young patient, a tonic pupil was associated with a benign orbital mass.

摘要

目的/方法：幼儿期的强直性瞳孔较为罕见。我们研究了一名3个半月大的健康女童，其右侧瞳孔对光反应迟钝，无动眼神经麻痹的其他体征。

结果/结论：滴入0.125%毛果芸香碱滴眼液后右侧瞳孔收缩，证实为去神经超敏反应，符合强直性瞳孔表现。无斜视或眼球突出。磁共振成像扫描显示右侧眶内有一肿块，位于外直肌和下直肌之间。活检结果符合良性神经胶质-神经错构瘤。因此，在这名年轻患者中，强直性瞳孔与眶内良性肿块有关。