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[心房颤动的外科治疗]

[Surgical treatment of atrial fibrillation].

作者信息

Fauchier J P, Fauchier L, Babuty D, Cosnay P, Rouesnel P, Aupart M

机构信息

Service de cardiologie B et laboratoire d'électrophysiologie cardiaque, hôpital Trousseau, Tours.

出版信息

Arch Mal Coeur Vaiss. 1994 Sep;87 Spec No 3:69-73.

PMID:7786127
Abstract

The persistence of atrial fibrillation with a controlled ventricular response with medical treatment or ablation of the His bundle, suppresses troublesome palpitations but leaves potential haemodynamic problems and the risk of thromboembolism. Surgical treatment of this arrhythmia, by leaving an anatomic bridge between the sinus and atrioventricular nodes, aims to allow acceleration of the ventricular rhythm on exercise whilst preventing by partial, total or selective exclusion of atrial tissues, the multiple intra-atrial reentries responsible for atrial flutter or fibrillation. The first method proposed was isolation of the left atrium (Cox, 1980) which allows acceleration of the ventricular rhythm during exercise, leaving little or no haemodynamic disturbance, but, in theory, the same risk of embolism. The second method, the "corridor" operation (Guiraudon, 1985) consists in isolating both atria, but significantly alters the haemodynamic efficacy without reducing the embolic risk, and hardly offers any advantage over ablation of the nodo-hisian pathway completed by implantation of a ventricular, rate responsive, pacemaker. The recently described "maze" procedure (Cox and Boineau, 1991) would seem to be more promising with judiciously chosen incisions (at the base of the atria, around the pulmonary veins, between the vena cavae, along the interatrial septum, etc.) and points of cryoablation in the region of the coronary sinus, allowing modulation of the ventricular response with activation of sufficient atrial tissue to prevent reentry and recurrence of atrial fibrillation without affecting haemodynamic efficacy. The results of this technique are encouraging in the hands of its inventors but require confirmation in larger series of patients.(ABSTRACT TRUNCATED AT 250 WORDS)

摘要

药物治疗或希氏束消融控制心室率的情况下房颤仍持续存在,虽能抑制令人烦恼的心悸,但会遗留潜在的血流动力学问题和血栓栓塞风险。这种心律失常的外科治疗通过在窦房结和房室结之间保留解剖学桥接,旨在使运动时心室率加快,同时通过部分、完全或选择性排除心房组织,预防导致心房扑动或房颤的多个心房内折返。最初提出的方法是左心房隔离术(考克斯,1980年),该方法可使运动时心室率加快,几乎不产生或仅产生极小的血流动力学干扰,但理论上存在相同的栓塞风险。第二种方法是“走廊”手术(吉劳东,1985年),即隔离双侧心房,但会显著改变血流动力学效果且不降低栓塞风险,与植入心室频率应答起搏器完成希氏束 - 希氏束径路消融相比几乎没有优势。最近描述的“迷宫”手术(考克斯和博伊诺,1991年)似乎更具前景,通过明智地选择切口(在心房底部、肺静脉周围、腔静脉之间、沿房间隔等)以及在冠状窦区域进行冷冻消融点,在激活足够心房组织以预防折返和房颤复发的同时调节心室反应,而不影响血流动力学效果。该技术在发明者手中的结果令人鼓舞,但需要在更多患者系列中得到证实。(摘要截断于250字)

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