来自黑脑袋瓜（Cabeça-de-negro）的葫芦素糖苷。

Cucurbitacin glycosides from Cabeça-de-negro.

作者信息

Nakano K, Kanai Y, Murakami K, Takaishi Y

机构信息

Faculty of Pharmaceutical Sciences, Tokushima University, Japan.

出版信息

Phytochemistry. 1995 May;39(1):209-11. doi: 10.1016/0031-9422(94)00869-u.

DOI:10.1016/0031-9422(94)00869-u

PMID:7786489

Abstract

Five cucurbitacin glycosides named cabenosides D-L were isolated from 'Cabeça-de-negro', the roots of Caput nigri. Among them, the structures of cabenosides D-H were elucidated as 10 alpha-cucurbit-5-en-11-oxo-3 beta,24R,25-triol-3-O-beta-D-glucopyranoside, 10 alpha-cucurbit-5-en-24-oxo-3 beta, 11 alpha,25-triol-25-O-beta-D- glucopyranosyl, [3,O-beta-D-glucopyranoside, 3-O-beta-D-glucopyranosyl-(1-2)-beta-D-glucopyranoside, 3-O-beta-D-glucopyranosyl-(1-6)-beta-D-glucopyranoside] and 10 alpha-cucurbit-5-en-11,24-dioxo-3 beta,25-diol-25-O-beta-D- glucopyranosyl, 3-O-beta-D-glucopyranosyl-(1-6)-beta-D-glucopyranoside, respectively, on the basis of chemical and spectral evidence.

摘要

从黑首（Caput nigri）的根“Cabeça-de-negro”中分离出了五种名为卡贝诺苷D-L的葫芦素糖苷。其中，基于化学和光谱证据，卡贝诺苷D-H的结构分别被阐明为10α-葫芦-5-烯-11-氧代-3β,24R,25-三醇-3-O-β-D-吡喃葡萄糖苷、10α-葫芦-5-烯-24-氧代-3β,11α,25-三醇-25-O-β-D-吡喃葡萄糖基，[3,O-β-D-吡喃葡萄糖苷、3-O-β-D-吡喃葡萄糖基-(1→2)-β-D-吡喃葡萄糖苷、3-O-β-D-吡喃葡萄糖基-(1→6)-β-D-吡喃葡萄糖苷]以及10α-葫芦-5-烯-11,24-二氧代-3β,25-二醇-25-O-β-D-吡喃葡萄糖基、3-O-β-D-吡喃葡萄糖基-(1→6)-β-D-吡喃葡萄糖苷。