来自白首乌的14,15-断-18-降孕甾烷系列甾体糖苷。

Steroidal glycosides of the 14,15-seco-18-nor-pregnane series from Cynanchum ascyrifolium.

作者信息

Yeo H, Kim K W, Kim J, Choi Y H

机构信息

College of Pharmacy, Seoul National University, Korea.

出版信息

Phytochemistry. 1998 Oct;49(4):1129-33. doi: 10.1016/s0031-9422(97)01064-9.

DOI:10.1016/s0031-9422(97)01064-9

PMID:9788147

Abstract

Three new steroidal glycosides named cynascyrosides A-C were isolated from the roots of Cynanchum ascyrifolium. The structures of these compounds were determined on the basis of spectroscopic and chemical evidence as cynajapogenin A 3-O-alpha-D-oleandropyranosyl-(1-->4)-beta-L-cymaropyranosyl -(1-->4)-beta-D- digitoxopyranoside; cynajapogenin A 3-O-beta-D-glucopyranosyl-(1-->4)-alpha-L-cymaropyranosyl- (1-->4)-beta-L-cymaropyranosyl-(1-->4)-beta-L-cymaropyranoside+ ++; cynajapogenin A 3-O-beta-D-glucopyranosyl-(1-->4)-alpha-L-cymaropyranosyl- (1-->4)-beta-D-digitoxopyranosyl-(1-->4)-beta-L-cymaropyranosid e.

摘要

从白薇（Cynanchum ascyrifolium）的根中分离出三种新的甾体糖苷，命名为白薇糖苷A - C。基于光谱和化学证据确定这些化合物的结构分别为：cynajapogenin A 3 - O - α - D - 夹竹桃吡喃糖基 - (1→4) - β - L - 磁麻吡喃糖基 - (1→4) - β - D - 洋地黄毒吡喃糖苷；cynajapogenin A 3 - O - β - D - 葡萄糖吡喃糖基 - (1→4) - α - L - 磁麻吡喃糖基 - (1→4) - β - L - 磁麻吡喃糖基 - (1→4) - β - L - 磁麻吡喃糖苷；cynajapogenin A 3 - O - β - D - 葡萄糖吡喃糖基 - (1→4) - α - L - 磁麻吡喃糖基 - (1→4) - β - D - 洋地黄毒吡喃糖基 - (1→4) - β - L - 磁麻吡喃糖苷。