Balkin J, Rosenmann D, Ilan M, Klutstein M, Zion M M, Abraham A S
Department of Cardiology, Shaare Zedek Medical Center, Jerusalem, Israel.
Magnes Res. 1994 Dec;7(3-4):267-71.
A total of 266 patients entered into a study comparing the effect of intravenous magnesium and propranolol following acute myocardial infarction. Of these, 97 were able to receive either drug and were therefore randomized into the magnesium (n = 51) or propranolol group (n = 46). 88 patients were unable to receive propranolol and formed a third group (NR) while a further 81 patients could not receive either drug and formed a fourth group (N). The study showed that intravenous magnesium was as effective in preventing potentially lethal arrhythmias as propranolol and could be given to some 70 per cent of such patients whereas propranolol could only be given to 36 per cent.
共有266名患者参与了一项比较急性心肌梗死后静脉注射镁和普萘洛尔效果的研究。其中，97名患者能够接受这两种药物中的任何一种，因此被随机分为镁治疗组（n = 51）或普萘洛尔组（n = 46）。88名患者无法接受普萘洛尔，组成第三组（NR），另有81名患者两种药物都无法接受，组成第四组（N）。研究表明，静脉注射镁在预防潜在致命性心律失常方面与普萘洛尔一样有效，约70%的此类患者可以使用，而普萘洛尔只能用于36%的患者。
