Lacroix H, Boel K, Nevelsteen A, Suy R
Department of Vascular Surgery, Universitaire Ziekenhuizen KUL, Katholieke Universiteit, Leuven, Belgium.
Ann Vasc Surg. 1995 Mar;9(2):152-4. doi: 10.1007/BF02139657.
The immediate inflammatory response following aortic reconstruction with two types of sealed Dacron grafts was studied in a prospective, randomized manner. C-reactive protein (CRP) levels were measured before surgery and on days 2 and 8 postoperatively. In the collagen-sealed group (n = 10) CRP levels were 10 +/- 9.6, 180.2 +/- 48.3, and 54.3 +/- 34.3 mg/L, respectively. In the gelatin-impregnated group (n = 10) the values were 10.5 +/- 8.7, 200.7 +/- 27.3, and 80.3 +/- 30.2 mg/L, respectively. The slight differences were not significant according to the analysis of variance test for repeated measurements. These findings suggest that implantation of a knitted Dacron graft sealed with collagen does not lead to a higher inflammatory reaction compared with a gelatin-sealed graft.
采用前瞻性随机方法研究了两种密封涤纶移植物进行主动脉重建后的即时炎症反应。在手术前以及术后第2天和第8天测量C反应蛋白（CRP）水平。在胶原密封组（n = 10）中，CRP水平分别为10±9.6、180.2±48.3和54.3±34.3mg/L。在明胶浸渍组（n = 10）中，数值分别为10.5±8.7、200.7±27.3和80.3±30.2mg/L。根据重复测量的方差分析检验，这些微小差异无统计学意义。这些发现表明，与明胶密封移植物相比，植入胶原密封的针织涤纶移植物不会导致更高的炎症反应。
