人精浆中鸟嘌呤、鸟苷、肌苷和腺苷的含量

Abundance of guanine, guanosine, inosine and adenosine in human seminal plasma.

作者信息

Fabiani R, Ronquist G

机构信息

Department of Clinical Chemistry, University Hospital, University of Uppsala, Sweden.

出版信息

Int J Clin Lab Res. 1995;25(1):47-51. doi: 10.1007/BF02592577.

DOI:10.1007/BF02592577

PMID:7787211

Abstract

Guanine, guanosine, inosine and adenosine were found in large amounts in seminal plasma from 145 men, regardless of whether spermatozoa were present or not. The mean guanine level in 61 normozoospermic men was 89.7 +/- 93.1 mumol/l; this was significantly lower in 32 vasectomized men (18.9 +/- 31 mumol/l) suggesting the involvement of the epididymis in its secretion. Guanine and nucleoside levels were significantly higher in the seminal plasma of oligozoo- and azoospermic than normozoospermic men. Guanine and nucleoside levels were consistently inter-related in the seminal plasma of normozoospermic men with the best correlation between guanine and guanosine.

摘要

在145名男性的精浆中发现大量鸟嘌呤、鸟苷、肌苷和腺苷，无论其中是否存在精子。61名精子正常的男性精浆中鸟嘌呤的平均水平为89.7±93.1μmol/l；32名输精管结扎男性的该水平显著较低（18.9±31μmol/l），表明附睾参与了其分泌。少精子症和无精子症男性精浆中的鸟嘌呤和核苷水平显著高于精子正常的男性。在精子正常的男性精浆中，鸟嘌呤和核苷水平始终相互关联，其中鸟嘌呤与鸟苷之间的相关性最佳。