USF - 19A，一种来自链霉菌属的新型脂氧合酶抑制剂。
USF-19A, a new lipoxygenase inhibitor from Streptomyces sp.
作者信息
Komoda T, Morimitsu Y, Hirota H, Hirota A
机构信息
Laboratory of Applied Microbiology, School of Food and Nutritional Sciences, University of Shizuoka, Japan.
出版信息
Biosci Biotechnol Biochem. 1995 May;59(5):924-6. doi: 10.1271/bbb.59.924.
PMID:7787309
Abstract
USF-19A, a soybean lipoxygenase (SBL) and human 5-lipoxygenase (5-LO) inhibitor, was isolated from Streptomyces sp. USF-19 strain. Its chemical structure was determined by spectroscopic evidence to be a new member of the antimycin antibiotic family. The IC50 value of USF-19A against 5-LO was 28.0 microM.
摘要
USF-19A是一种大豆脂氧合酶（SBL）和人5-脂氧合酶（5-LO）抑制剂，从链霉菌属USF-19菌株中分离得到。通过光谱证据确定其化学结构为抗霉素抗生素家族的一个新成员。USF-19A对5-LO的IC50值为28.0微摩尔。
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