Tiunov L A
Vestn Ross Akad Med Nauk. 1995(3):9-13.
This paper considers the mechanisms of energy-dependent and synchronized detoxication and antioxidative defense (AOD) when synchronized detoxication and antioxidative defense (AOD) when the body is exposed to chemicals. It emphasizes the role of glutathione as a binder of this system involving in the regulation of this activity. It also discusses the mechanisms that define the reliability and efficiency of detoxication and AOD. The paper discusses whether the body's resistance to technogenic toxicants can be enhanced by using metabolic precursors of glutathione and other natural and (or) synthetic agents activating natural detoxication and AOD.
本文探讨了机体接触化学物质时能量依赖型同步解毒与抗氧化防御（AOD）的机制。强调了谷胱甘肽作为该系统结合剂在调节此活性过程中的作用。还讨论了决定解毒和AOD可靠性及效率的机制。本文探讨了使用谷胱甘肽的代谢前体以及其他激活天然解毒和AOD的天然和（或）合成剂是否能增强机体对技术源毒物的抵抗力。
