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[早产风险妊娠预后评估的判别分析模型]

[Discriminant analytic model for prognostic assessment of pregnancies at risk for premature labor].

作者信息

Faber R, Viehweg B, Hiller K

机构信息

Universitäts-Frauenklinik Leipzig.

出版信息

Z Geburtshilfe Neonatol. 1995 Mar-Apr;199(2):48-53.

PMID:7788577
Abstract

We examined 114 women with preterm labor using discriminance analysis to assess predictive values in terms of prolongation of gestational age and gestational age at the time of delivery. We used parameters like medical history, clinical features, infections, Doppler sonography and cardiotocography. Maternal temperature, cardiotocographic findings, premature rupture of membranes, number of abortions and pregnancy terminations and cervical dilatation at the time of admission contribute significantly to predict prolongation of pregnancy (< or = as well as > 7 days). Our results from this analysis showed sensitivity and specificity of 0.70 and 0.97 and positive and negative predictive values of 0.89 and 0.91, respectively. We observed significant differences concerning parameters like preterm rupture of membranes, cervical dilatation, pathological bacteria in the vagina and pathological Doppler values between subsequent preterm and term deliveries in pregnancies with a prolongation of > 7 days was. Upon reclassifying our results, we obtained sensitivity and specificity of 0.69 and 0.89 and positive and negative predictive values of 0.78 and 0.84, respectively. Early prognostic assessment of preterm labor can be made with discriminance analysis. The results inspire us to perform a prospective examination of the therapy plan that we have obtained.

摘要

我们使用判别分析对114例早产女性进行了检查,以评估其对孕周延长及分娩时孕周的预测价值。我们采用了病史、临床特征、感染情况、多普勒超声检查及胎心监护等参数。产妇体温、胎心监护结果、胎膜早破、流产及终止妊娠次数以及入院时宫颈扩张情况对预测妊娠延长(≤以及>7天)有显著作用。本次分析结果显示,敏感性和特异性分别为0.70和0.97,阳性预测值和阴性预测值分别为0.89和0.91。我们观察到,孕周延长>7天的妊娠中,后续早产与足月分娩在胎膜早破、宫颈扩张、阴道病原菌及病理性多普勒值等参数方面存在显著差异。重新分类我们的结果后,敏感性和特异性分别为0.69和0.89,阳性预测值和阴性预测值分别为0.78和0.84。早产的早期预后评估可通过判别分析进行。这些结果促使我们对所获得的治疗方案进行前瞻性研究。

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