Liu D, Ling Q, Venkataseshan V S
Department of Pathology, Bengpu Medical College.
Zhongguo Ji Sheng Chong Xue Yu Ji Sheng Chong Bing Za Zhi. 1995;13(1):64-7.
Eighteen autopsy cases of acquired toxoplasmosis in New York City were studied. Seventeen cases were with acquired immunodeficiency syndrome (AIDS) and one patient with Hodgkin's disease. All 18 cases involved the brain and nine of them disseminated to the heart (8 cases), lung (4 cases), pancreas (3 cases), alimentary tract (2 cases) and urogenital organs (3 cases). The authors divided the acquired toxoplasmosis into (1) immunocompetent, (2) immunocompromised and (3) immunodeficient types. The autopsy findings showed that the brain, heart and lung were the most susceptible organs. Pseudocysts were also found in lungs and alimentary tract, suggesting an autoinfection by swallowing sputum containing Toxoplasma. Toxoplasma in the urogenital organs might become a source for sexual transmitted toxoplasmosis.
对纽约市18例获得性弓形虫病尸检病例进行了研究。其中17例患有获得性免疫缺陷综合征(艾滋病),1例患有霍奇金病。所有18例均累及脑部,其中9例扩散至心脏(8例)、肺(4例)、胰腺(3例)、消化道(2例)和泌尿生殖器官(3例)。作者将获得性弓形虫病分为(1)免疫功能正常型、(2)免疫功能受损型和(3)免疫缺陷型。尸检结果显示,脑、心脏和肺是最易受影响的器官。在肺和消化道中也发现了假包囊,提示可能通过吞咽含有弓形虫的痰液而发生自身感染。泌尿生殖器官中的弓形虫可能成为性传播弓形虫病的传染源。