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[艾滋病患者脑外弓形虫病的免疫组织化学证明]

[Immunohistochemical demonstration of extracerebral toxoplasmosis in AIDS].

作者信息

Jautzke G, Sell M, Thalmann U, Janitschke K, Iglesias J, Schürmann B, Ruf B

机构信息

Pathologisches Institut, Universitätsklinikums Rudolf Virchow, Standort Wedding, Berlin.

出版信息

Verh Dtsch Ges Pathol. 1991;75:185-8.

PMID:1724828
Abstract

Tissue slides obtained at autopsy from 80 cases with AIDS were studied immunhistochemically for infection with Toxoplasma gondii. In 35 cases (43.75%) toxoplasmosis could be found: in 22 cases (27.5%) only cerebral, in 9 cases (11.25%) cerebral and extracerebral and in 4 cases (5%) only extracerebral. Necrotizing lesions, due to the parasite could be seen in brain, heart, lungs, pancreas, adrenal glands and testis, only intracellular trophozoites without tissue damage in GIT, liver, lymphnodes, spleen, prostate, kidney and gl. parotis. The trophozoites and pseudocysts could be clearly demonstrated by immunohistochemistry.

摘要

对80例艾滋病尸检获得的组织切片进行免疫组织化学研究,以检测是否感染弓形虫。在35例(43.75%)中发现有弓形虫病:22例(27.5%)仅累及脑部,9例(11.25%)脑部和脑外均有累及,4例(5%)仅累及脑外。在脑、心脏、肺、胰腺、肾上腺和睾丸中可见由寄生虫引起的坏死性病变,而在胃肠道、肝脏、淋巴结、脾脏、前列腺、肾脏和腮腺中仅见细胞内滋养体,无组织损伤。通过免疫组织化学可清楚显示滋养体和假包囊。

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