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[评估催产素用于引产对新生儿黄疸发生率和严重程度的影响]

[Evaluation of the effect of oxytocin use for labor induction on frequency of occurrence and severity of neonatal jaundice].

作者信息

Woytoń J, Agrawal P, Zimmer M

机构信息

II Katedry i Kliniki Połoznictwa AM we Wrocławiu.

出版信息

Ginekol Pol. 1994 Dec;65(12):682-5.

PMID:7789859
Abstract

Authors conducted analysis of effect of method used (which consisted of use of oxytocin, vit B, oestradiol) for labour induction on frequency of occurrence and severity of neonatal jaundice on 3rd day of neonatal life. Analysed material consisted of 1154 deliveries between the years 1990 to 1992 in IInd Department of Obstetrics AM Wrocław. Only completely physiological pregnancies qualified for analysis. The above mentioned sum of analysed deliveries was divided into 2 groups. Ist group consisted of 801 normal deliveries without any oxytocin use 2nd group consisted of 353 normal deliveries during which i.v. oxytocin drip was used either for induction of labour or to intensify uterine contraction during labour. Evaluation of the above data do not show significant increase in cases with hyperbilirubinemia in group with labour induction (7%) in comparison with deliveries without oxytocin use (5%). Moreover eliminating from the analysis cases of jaundice with normal bilirubin level (12 mg%), I degree jaundice, the actual count of cases of hyperbilirubinemia in group without oxytocin use in 26 (3.24%) and in group with oxytocin use is 13 (3.67%) cases (Tab. IV) which is not a significant difference and does not permit us to conclude that oxytocin use for labour induction is responsible for increased frequency of neonatal hyperbilirubinemia.

摘要

作者对用于引产的方法(包括使用催产素、维生素B、雌二醇)对新生儿出生后第3天黄疸发生频率和严重程度的影响进行了分析。分析材料包括1990年至1992年在弗罗茨瓦夫第二产科进行的1154例分娩。只有完全生理性妊娠才符合分析条件。上述分析的分娩总数分为2组。第一组由801例未使用任何催产素的正常分娩组成,第二组由353例正常分娩组成,在这些分娩过程中,静脉滴注催产素用于引产或加强分娩时的子宫收缩。对上述数据的评估显示,引产组(7%)高胆红素血症病例与未使用催产素的分娩组(5%)相比没有显著增加。此外,从分析中排除胆红素水平正常(12mg%)的黄疸病例、I度黄疸病例后,未使用催产素组高胆红素血症实际病例数为26例(3.24%),使用催产素组为13例(3.67%)(表IV),这一差异不显著,也不能使我们得出引产使用催产素会导致新生儿高胆红素血症发生率增加的结论。

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