Klinger M, Danter J, Siegert R, Moubayed P
Klinik für Hals-, Nasen- und Ohrenheilkunde, Medizinischen Universität zu Lübeck.
HNO. 1995 Apr;43(4):253-6.
According to its morphological appearance, Kikuchi's disease is also called "histiocytic necrotizing lymphadenitis". This disorder was first described in Japan in 1972 as a benign lymphadenopathy of the neck. In Germany only a few cases have been reported by pathologists, whereas most clinicians are unaware of the existence of this rare disease, which can easily be mistaken for malignant lymphoma. In 1993 three cases of Kikuchi's lymphadenitis were treated at the ENT Department of the University of Lübeck. Patients' ages ranged from 15 to 30 years old. Except for cervical adenopathy, findings in blood tests, viral serology and radiological imaging were unremarkable. While fine needle aspirations were suspicious for malignant lymphoma, a final diagnosis of self-limiting "Kikuchi's lymphadenitis" was established histologically from excised lymph nodes. In our opinion early extirpation of lymph nodes and consultation of a pathologist are necessary to make a correct diagnosis without delay. Thus, in patients with Kikuchi's lymphadenitis unnecessary staging procedures and treatment can be avoided.
根据其形态学表现，菊池病也被称为“组织细胞坏死性淋巴结炎”。这种疾病于1972年在日本首次被描述为颈部的一种良性淋巴结病。在德国，病理学家仅报告了少数病例，而大多数临床医生并不知晓这种罕见疾病的存在，它很容易被误诊为恶性淋巴瘤。1993年，吕贝克大学耳鼻喉科治疗了3例菊池淋巴结炎患者。患者年龄在15至30岁之间。除颈部淋巴结病外，血液检查、病毒血清学和放射影像学检查结果均无异常。虽然细针穿刺活检怀疑为恶性淋巴瘤，但通过切除淋巴结的组织学检查最终确诊为自限性的“菊池淋巴结炎”。我们认为，早期切除淋巴结并咨询病理学家对于及时做出正确诊断是必要的。因此，对于菊池淋巴结炎患者，可以避免不必要的分期检查和治疗。
