一名类风湿关节炎患者在接受甲氨蝶呤治疗时发生单核细胞增生李斯特菌感染。
Listeria monocytogenes infection in a patient treated with methotrexate for rheumatoid arthritis.
作者信息
McCambridge M M, Vogelgesang S A, Ockenhouse C F
机构信息
Department of Medicine, Walter Reed Army Medical Center, Washington, DC 20307-5000, USA.
出版信息
J Rheumatol. 1995 Apr;22(4):786-7.
PMID:7791185
Abstract
We describe a patient with rheumatoid arthritis who developed bacteremia from Listeria monocytogenes after treatment with low dose oral pulse methotrexate. We discuss possible immunologic mechanisms for susceptibility to Listeria infections. As the elderly population increases with more frequent use of immunosuppressive medications, clinical suspicion must be maintained to correctly diagnose and treat infections such as Listeria.
摘要
我们描述了一名类风湿性关节炎患者，其在接受低剂量口服脉冲甲氨蝶呤治疗后发生了单核细胞增生李斯特菌引起的菌血症。我们讨论了对李斯特菌感染易感性的可能免疫机制。随着老年人口增加以及免疫抑制药物使用更加频繁，必须保持临床怀疑以正确诊断和治疗诸如李斯特菌感染等疾病。
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