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[通过尿抗原检测诊断的军团菌肺炎]

[Legionella pneumonia diagnosed by urinary antigen detection].

作者信息

Yoshizawa A, Kotajima F, Sugiyama H, Kudo K, Yagishita Y, Kabe J

机构信息

Department of Pulmonary Medicine, International Medical Center of Japan.

出版信息

Nihon Kyobu Shikkan Gakkai Zasshi. 1995 Apr;33(4):468-72.

PMID:7791279
Abstract

A 63-year-old man with dyspnea and high fever was admitted to the hospital. A pneumonic shadow in the right lower lung field was observed. After administration of rifampicin and clarithromycin, his symptoms were gradually alleviated. Although Legionella pneumonia was highly suspected, Legionella pneumophila was not isolated from his sputum specimens and the serum level of indirect immunofluorescent antibody titer was not significantly elevated. However, we believe it is very likely that he had Legionella pneumonia, because we detected a high density of urinary Legionella pneumophila serogroup 1 antigen by antigen capture EIA.

摘要

一名63岁男性因呼吸困难和高热入院。右下肺野可见肺炎阴影。给予利福平和克拉霉素治疗后,他的症状逐渐缓解。尽管高度怀疑为军团菌肺炎,但痰标本未分离出嗜肺军团菌,间接免疫荧光抗体滴度的血清水平也未显著升高。然而,我们认为他很可能患有军团菌肺炎,因为通过抗原捕获酶免疫测定法检测到尿中嗜肺军团菌血清1型抗原密度很高。

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