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对SAS嗜肺军团菌检测法的评估,这是一种用于检测尿液中嗜肺军团菌血清1型抗原的新型免疫层析测定法。

Evaluation of the SAS Legionella Test, a new immunochromatographic assay for the detection of Legionella pneumophila serogroup 1 antigen in urine.

作者信息

Diederen B M W, Peeters M F

机构信息

Laboratory for Medical Microbiology and Immunology, St Elisabeth Hospital, Tilburg, The Netherlands.

出版信息

Clin Microbiol Infect. 2007 Jan;13(1):86-8. doi: 10.1111/j.1469-0691.2006.01587.x.

Abstract

This study evaluated a new immunochromatographic assay (SAS Legionella Test) for its ability to detect Legionella pneumophila serogroup 1 antigen in urine. Results were compared with those obtained using the Binax Now urinary antigen test. Sensitivity and specificity were estimated as 82.9% and 99.0%, respectively, for the SAS Legionella Test, and 91.4% and 100%, respectively, for the Binax Now urinary antigen test. The sensitivity of both tests increased to 97.1% (p 0.009) and 94.2% (p 0.7), respectively, if the tests were examined after 1 h.

摘要

本研究评估了一种新型免疫层析检测法(SAS嗜肺军团菌检测)检测尿液中嗜肺军团菌血清1型抗原的能力。将结果与使用Binax Now尿抗原检测法所获结果进行比较。SAS嗜肺军团菌检测法的敏感性和特异性估计分别为82.9%和99.0%,而Binax Now尿抗原检测法的敏感性和特异性分别为91.4%和100%。如果在1小时后进行检测,两种检测法的敏感性分别提高到97.1%(p<0.009)和94.2%(p<0.7)。

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