La Placa G, Andreotti M, Arlati S, Urbano M
Divisione di Pediatria, USSL 63-Ospedale di Desio, Desio Milano.
Minerva Pediatr. 1995 Mar;47(3):93-5.
The authors describe two cases of benign transient hyperphosphatesamia of infancy. This form is not so frequent in childhood and the following criteria must be present for a correct diagnosis: 1) Patient age of less than 5 years. 2) Variable symptoms. 3) No bone or liver disease noted on physical examination. 4) No other biochemical or laboratory evidence for bone or liver disease. 5) A return to normal serum alkaline phosphatase levels within 4 months with no sequelae. We want underline the uselessness of vitamin D therapy and the importance of a deepened study about biochemical and laboratory parameters in all patients affected by alkaline hyperphosphatesamia, to exclude a possible severe disease.
作者描述了两例婴儿期良性短暂性高磷酸盐血症。这种形式在儿童期并不常见,正确诊断必须具备以下标准:1)患者年龄小于5岁。2)症状多样。3)体格检查未发现骨骼或肝脏疾病。4)没有其他骨骼或肝脏疾病的生化或实验室证据。5)血清碱性磷酸酶水平在4个月内恢复正常且无后遗症。我们想强调维生素D治疗的无用性,以及对所有受碱性高磷酸盐血症影响的患者进行生化和实验室参数深入研究的重要性,以排除可能的严重疾病。