Garty B, Stayer D, Harell D, Cornblut B, Nitzan M
Pediatrics Dept., Beilinson Medical Center, Petah Tikva.
Harefuah. 1992 Dec 15;123(12):519-21, 572.
Transient hyperphosphatasemia of infancy was diagnosed in 4 children hospitalized during a 6-month period (0.3% of all hospitalized children). The characteristic features of this disorder are: 1. elevation of serum alkaline phosphatase (of both liver and bone origin) up to 3-30 times the upper limit of normal for age (usually discovered during intercurrent infection); 2. return of the serum alkaline phosphatase to normal in a few weeks; 3. no residual clinical or laboratory evidence of bone or liver disease. The child is usually less than 5 years old. Recognition of the benign nature of this disorder prevents extensive laboratory workup and unnecessary anxiety.
6个月内，4名住院儿童被诊断为婴儿期短暂性高磷酸酶血症（占所有住院儿童的0.3%）。这种疾病的特征如下：1. 血清碱性磷酸酶（来自肝脏和骨骼）升高至年龄正常上限的3至30倍（通常在并发感染期间发现）；2. 血清碱性磷酸酶在几周内恢复正常；3. 没有骨骼或肝脏疾病的残留临床或实验室证据。患儿通常小于5岁。认识到这种疾病的良性性质可避免进行广泛的实验室检查和不必要的焦虑。
