Mizukami Y, Nonomura A, Michigishi T, Ohmura K, Matsubara S, Noguchi M
Pathology Section, Kanazawa University Hospital, Japan.
Pathol Res Pract. 1994 Dec;190(12):1201-5; discussion 1206-7. doi: 10.1016/S0344-0338(11)80448-6.
A rare case of a patients with sarcoidosis of the thyroid gland, who was preoperatively diagnosed as having thyroid carcinoma and who had no other clinical features of sarcoidosis, is reported. Thyroidectomy specimen revealed numerous noncaseating, epithelioid granulomas in the thyroid tissue. Mycobacteria, fungi and foreign body material were not identified. Similar granulomas were also found in the lymph nodes and muscular tissue adjacent to the thyroid gland and parathyroid gland After the diagnosis of sarcoidosis of the thyroid, systemic examination failed to reveal any involvement in other sites, including lung, eye and skin. This case demonstrated that sarcoidosis can manifest initially as a thyroid tumor with no other evidence of disease.
本文报告了一例罕见的甲状腺结节病患者,该患者术前被诊断为甲状腺癌,且无结节病的其他临床特征。甲状腺切除标本显示甲状腺组织中有大量非干酪样上皮样肉芽肿。未发现分枝杆菌、真菌和异物。在甲状腺和甲状旁腺附近的淋巴结和肌肉组织中也发现了类似的肉芽肿。在诊断为甲状腺结节病后,全身检查未发现其他部位有任何受累,包括肺、眼和皮肤。该病例表明,结节病最初可表现为甲状腺肿瘤,而无其他疾病证据。