Miller D J, Kotses H
Department of Psychology and Sociology, South Carolina State University, Orangeburg 29117, USA.
Psychosom Med. 1995 Mar-Apr;57(2):148-53. doi: 10.1097/00006842-199503000-00007.
A differential classical conditioning paradigm was used to investigate changes in total respiratory resistance in healthy adult female subjects. The conditioned stimuli were red and blue colors projected on a screen, and the unconditioned stimulus was an arithmetic task in which the subject mentally subtracted serial 17s from a number displayed on the screen. One of the two colors was paired with the arithmetic problem, and the other color was presented alone. Participants completed seven paired and seven unpaired trials. Both total respiratory resistance and functional residual capacity changes were measured before and during each conditioned stimulus. Total respiratory resistance was higher during the paired conditioned stimuli than it was during the unpaired conditioned stimuli. This result was not related to variations in functional residual capacity. It was concluded that elevated total respiratory resistance during the paired stimuli was a result of conditioning. The elevations were probably due to increases in bronchomotor tone. Conditioned changes in total respiratory resistance may be related to some respiratory behaviors both in healthy individuals and in patients with asthma.
采用差异经典条件反射范式来研究健康成年女性受试者总呼吸阻力的变化。条件刺激是投射在屏幕上的红色和蓝色，非条件刺激是一项算术任务，即受试者在脑海中从屏幕上显示的数字中依次减去17。两种颜色中的一种与算术问题配对，另一种颜色单独呈现。参与者完成了七次配对试验和七次非配对试验。在每个条件刺激之前和期间都测量了总呼吸阻力和功能残气量的变化。配对条件刺激期间的总呼吸阻力高于非配对条件刺激期间。这一结果与功能残气量的变化无关。得出的结论是，配对刺激期间总呼吸阻力升高是条件反射的结果。升高可能是由于支气管运动张力增加。总呼吸阻力的条件性变化可能与健康个体和哮喘患者的某些呼吸行为有关。
