Kay L, Jørgensen T, Jensen K H
Amtssygehuset i Glostrup.
Ugeskr Laeger. 1995 Jun 12;157(24):3476-80.
With the aim to assess prevalence, incidence, recovery and risk factors of irritable bowel syndrome a follow-up study of 4581 Danes was carried out. The cohort was obtained by a sex- and age-stratified random sample of Danes living in the Western part of Copenhagen County. Participants were interviewed about abdominal symptoms. According to various definitions, the prevalence of irritable bowel syndrome varied from 5 to 65% and the incidence varied from 1 to 36%. At the five year follow-up only 5% of subjects with irritable bowel syndrome were free of all symptoms. Psychic vulnerability, female sex, younger age and having problems were strongly associated to irritable bowel syndrome, while lifestyle factor were not important risk factors. Populations defined as suffering from irritable bowel syndrome according to various definitions had less than 50% of subjects in common. It is concluded that irritable bowel symptoms are frequent, fluctuating phenomena in the general population. Women, the young, the psychic vulnerable, and people having problems are at greater risk of having irritable bowel syndrome. Different studies applying different definitions of irritable bowel syndrome can not be considered to be comparable.
为评估肠易激综合征的患病率、发病率、康复情况及风险因素，对4581名丹麦人进行了一项随访研究。该队列通过对居住在哥本哈根县西部的丹麦人按性别和年龄分层随机抽样获得。参与者接受了关于腹部症状的访谈。根据不同的定义，肠易激综合征的患病率在5%至65%之间，发病率在1%至36%之间。在五年随访中，只有5%的肠易激综合征患者没有任何症状。心理易损性、女性、年轻以及有问题与肠易激综合征密切相关，而生活方式因素并非重要的风险因素。根据不同定义被界定为患有肠易激综合征的人群中，共同的受试者不到50%。结论是，肠易激症状在普通人群中很常见且波动较大。女性、年轻人、心理易损者以及有问题的人患肠易激综合征的风险更高。采用不同肠易激综合征定义的不同研究不能被认为具有可比性。
