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不对称乳头体:与内侧颞叶疾病的关联,磁共振成像显示

The asymmetric mamillary body: association with medial temporal lobe disease demonstrated with MR.

作者信息

Mamourian A C, Rodichok L, Towfighi J

机构信息

Department of Radiology, Dartmouth-Hitchock Medical Center, Lebanon, NH 03756, USA.

出版信息

AJNR Am J Neuroradiol. 1995 Mar;16(3):517-22.

Abstract

PURPOSE

To determine whether mamillary body atrophy is caused by deafferentation of the mamillary body in patients with mesial temporal sclerosis.

METHODS

We studied 36 patients with thin-section MR to assess mamillary body symmetry. These patients included 10 control subjects without seizures and 26 patients with a history of seizures. Thin-section T1 scans were available for all cases. The patients with epilepsy underwent axial and coronal T2 scans as well.

RESULTS

In five of eight cases with prior medial temporal lobe resection for intractable epilepsy, there was evidence of unilateral mamillary body atrophy ipsilateral to the resection. Similar findings were evident in three of six patients with MR findings of mesial temporal sclerosis without surgery. Two patients with medial temporal stroke or tumor also had ipsilateral mamillary body atrophy.

CONCLUSION

These findings provide support for the proposed mechanism of mamillary body atrophy caused by prior medial temporal lobe injury.

摘要

目的

确定内侧颞叶硬化患者乳头体萎缩是否由乳头体传入神经阻滞引起。

方法

我们对36例患者进行了薄层磁共振成像(MR)检查,以评估乳头体的对称性。这些患者包括10例无癫痫发作的对照受试者和26例有癫痫发作史的患者。所有病例均有薄层T1扫描图像。癫痫患者还进行了轴位和冠状位T2扫描。

结果

在8例因顽固性癫痫接受内侧颞叶切除术的患者中,有5例在切除同侧存在孤侧乳头体萎缩的证据。在6例有内侧颞叶硬化MR表现但未接受手术的患者中,有3例也有类似发现。2例内侧颞叶中风或肿瘤患者也有同侧乳头体萎缩。

结论

这些发现为先前内侧颞叶损伤导致乳头体萎缩的机制提供了支持。

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