Dimitrov R, Doganov N, Vasilev N, Iarŭkov A, Raĭcheva I
Akush Ginekol (Sofiia). 1994;33(3):19-21.
The study presents the results of urethral pressure profile measurements in 3 groups of women: continent nulliparous, continent parous and stress incontinent women. The maximum urethral closure pressure, the functional urethral length and the length of continence zone are compared. The healthy control groups (both parous and nulliparous) show much higher maximum urethral closure pressures than those mentioned in literature. No difference is evident between continent parous and continent nulliparous which suggests that vaginal delivery at term does not necessarily impair urethral sphincteric function. On the other hand women with similar age and parity with stress incontinence have a marked decrease of maximum urethral closure pressure at rest and demonstrate inability to increase it by volitional contraction of the pelvic floor. These findings support the idea of the leading role of sphincteric incompetence in stress incontinence. The functional urethral length and the length of continence zone show no significant differences among the investigated groups which implies that they are of no importance for the occurrence of stress incontinence.
尿失禁未生育女性、尿失禁经产妇和压力性尿失禁女性。比较了最大尿道闭合压、功能性尿道长度和控尿区长度。健康对照组（经产妇和未生育女性）的最大尿道闭合压远高于文献中提及的数值。尿失禁经产妇和尿失禁未生育女性之间没有明显差异，这表明足月阴道分娩不一定会损害尿道括约肌功能。另一方面，年龄和产次相似但患有压力性尿失禁的女性在静息时最大尿道闭合压显著降低，并且无法通过盆底自主收缩来提高该压力。这些发现支持了括约肌功能不全在压力性尿失禁中起主导作用的观点。在所研究的组中，功能性尿道长度和控尿区长度没有显著差异，这意味着它们对压力性尿失禁的发生并不重要。
