Spielmann M, Zelek L, Llombart A
Service de Médecine B, Institut Gustave-Roussy, Villejuif.
Arch Anat Cytol Pathol. 1995;43(1-2):73-6.
Breast sarcomas are rare, representing 1% of all malignant breast tumors. A variety of histologies are found, the main ones being fibrosarcomas and malignant fibrohistiocytomas. Nodal involvement is rare and, as in other sarcomas, hematogenous spread of metastases is more usual. Major prognostic factors are histological grade and mitotic activity; the three-year disease-free survival ranges between 40% and 60%. Surgery remains the treatment of choice of these tumors; for some authors adjuvant irradiation could improve local control, especially for patients treated with conservative surgery. The role of adjuvant chemotherapy remains undefined.
乳腺肉瘤较为罕见,占所有乳腺恶性肿瘤的1%。其可见多种组织学类型,主要为纤维肉瘤和恶性纤维组织细胞瘤。淋巴结受累情况少见,与其他肉瘤一样,血行转移更为常见。主要的预后因素是组织学分级和有丝分裂活性;三年无病生存率在40%至60%之间。手术仍然是这些肿瘤的首选治疗方法;一些作者认为辅助放疗可改善局部控制,特别是对于接受保乳手术的患者。辅助化疗的作用仍不明确。