Birnbacher R, Balzar E, Aufricht C, Schmaldienst S, Woloszczuk W, Förster E
Department of Paediatrics, University of Vienna, Austria.
Pediatr Nephrol. 1995 Apr;9(2):193-5. doi: 10.1007/BF00860744.
A 14-year-old boy with tubulointerstitial nephritis and uveitis (TINU syndrome) is described. Nephropathy improved without systemic cortisone treatment, whereas uveitis relapsed and was treated with topical steroids. Blood cell immunological analysis and serum analysis revealed signs of cytotoxic T-cell, macrophage and granulocyte activation, which declined as the clinical symptoms improved. This may be interpreted as an indication of their significance as markers in the pathogenesis of this syndrome or as part of a microbial-triggered immune response.
本文描述了一名患有肾小管间质性肾炎和葡萄膜炎（TINU综合征）的14岁男孩。肾病在未进行全身皮质类固醇治疗的情况下有所改善，而葡萄膜炎复发并接受了局部类固醇治疗。血细胞免疫分析和血清分析显示细胞毒性T细胞、巨噬细胞和粒细胞激活的迹象，这些迹象随着临床症状的改善而下降。这可能被解释为它们作为该综合征发病机制中的标志物或作为微生物触发的免疫反应一部分具有重要意义的一个指标。
