Hajjeh R A, Blumberg H M
Department of Medicine, Emory University School of Medicine, Atlanta, Georgia, USA.
Clin Infect Dis. 1995 Apr;20(4):913-6. doi: 10.1093/clinids/20.4.913.
Trichosporon beigelii is a yeast that has recently been increasingly associated with systemic infections in immunocompromised patients. Few cases have been reported in nonleukopenic patients. We describe what we believe to be the first report of a bloodstream infection due to T. beigelii in a burn patient. Our patient was successfully treated with a combination of amphotericin B and flucytosine. Antifungal susceptibility testing of the T. beigelii isolate showed that the organism was inhibited but not killed by amphotericin B. Burn patients are known to have a transient defect in neutrophil function that can predispose them to some infections. We review the English-language literature of recently reported cases of trichosporonosis and review the various therapies for T. beigelii infection.
白吉利丝孢酵母是一种酵母，最近越来越多地与免疫功能低下患者的全身感染相关。非白细胞减少患者中报道的病例很少。我们描述了我们认为是烧伤患者中首例由白吉利丝孢酵母引起的血流感染报告。我们的患者通过两性霉素B和氟胞嘧啶联合治疗成功治愈。对白吉利丝孢酵母分离株的抗真菌药敏试验表明，该菌被两性霉素B抑制但未被杀死。已知烧伤患者中性粒细胞功能存在短暂缺陷，这可能使他们易患某些感染。我们回顾了最近报道的毛孢子菌病病例的英文文献，并回顾了白吉利丝孢酵母感染的各种治疗方法。
