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气管切开术后狭窄。长期结果的定量研究。

Stenosis following tracheostomy. A quantitative study of long term results.

作者信息

Friman L, Hedenstierna G, Schildt B

出版信息

Anaesthesia. 1976 May;31(4):479-93. doi: 10.1111/j.1365-2044.1976.tb12353.x.

Abstract

Seventy out of the 320 patients treated with tracheostomy and respiratory care in an intensive care unit, were included in a follow-up study. A variety of surgical (38) and medical (32) conditions had prompted IPPV for 1-59 days; 33 had had primary and 37 secondary tracheostomies. The final study included an interview, physical examination, radiographic examination and spirometry. Using radiographic measures, the area of stenosis was calculated as well as the pressure drop across the stenosis at various flow rates. The methods of calculation were tested in one patient and compared with the actual tracheal pressure and gas flow recordings. Lateral stenosis was found in 69 and frontal stenosis in 25 patients, the length being 0-2-5-0 cm. The stenosis was situated at the level of the stoma in 59, at the cuff in 6, and at both sites in 2; in 2 the level could not be determined accurately. The mean area of normal trachea was 2-8+/-0-8 cm2 in females and 3-7+/-0-7 cm2 in males, while the stenotic area ranged from 0-86 to 4-54 cm2. A stenosis of potential functional significance was found in 8 patients (area less than 1-5 cm2). The stenotic area correlated well with the pressure drop across the stenosis and better than with the stenosis percentage (1-74%). The predicted pressure falls over the stenosis at different flow rates were in excellent agreement with those measured in one patient. Spirometry was unsuitable for detecting the stenosis. Poor correlation were found between the degree of tracheal stenosis and chronic respiratory disease, smoking, age, interval between intubation and tracheostomy, or duration of IPPV. Dysponea during moderate exercise was present in all patients who had a pronounced stenosis.

摘要

在一家重症监护病房接受气管切开术和呼吸护理的320名患者中,有70名被纳入一项随访研究。各种外科疾病(38例)和内科疾病(32例)促使患者进行了1至59天的间歇正压通气;33例行一期气管切开术,37例行二期气管切开术。最终研究包括访谈、体格检查、影像学检查和肺功能测定。采用影像学测量方法,计算狭窄面积以及不同流速下狭窄处的压力降。计算方法在一名患者身上进行了测试,并与实际气管压力和气体流量记录进行了比较。69例患者发现有侧方狭窄,25例有前方狭窄,长度为0.2至5.0厘米。59例狭窄位于造口水平,6例位于套管处,2例两处均有狭窄;2例狭窄水平无法准确确定。女性正常气管平均面积为2.8±0.8平方厘米,男性为3.7±0.7平方厘米,而狭窄面积在0.86至4.54平方厘米之间。8例患者发现有潜在功能意义的狭窄(面积小于1.5平方厘米)。狭窄面积与狭窄处压力降相关性良好,优于与狭窄百分比(1.74%)的相关性。不同流速下狭窄处预测压力降与一名患者测量值非常吻合。肺功能测定不适用于检测狭窄。气管狭窄程度与慢性呼吸道疾病、吸烟、年龄、插管与气管切开术间隔时间或间歇正压通气持续时间之间相关性较差。所有有明显狭窄的患者在适度运动时均出现呼吸困难。

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