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AML1 and the 8;21 and 3;21 translocations in acute and chronic myeloid leukemia.

作者信息

Nucifora G, Rowley J D

机构信息

Department of Medicine, University of Chicago, IL 60637, USA.

出版信息

Blood. 1995 Jul 1;86(1):1-14.

PMID:7795214
Abstract
摘要

相似文献

1
AML1 and the 8;21 and 3;21 translocations in acute and chronic myeloid leukemia.急性和慢性髓性白血病中的AML1以及8;21和3;21易位
Blood. 1995 Jul 1;86(1):1-14.
2
Intergenic splicing of MDS1 and EVI1 occurs in normal tissues as well as in myeloid leukemia and produces a new member of the PR domain family.MDS1和EVI1的基因间剪接在正常组织以及髓系白血病中均有发生,并产生PR结构域家族的一个新成员。
Proc Natl Acad Sci U S A. 1996 Feb 20;93(4):1642-7. doi: 10.1073/pnas.93.4.1642.
3
The AML1 gene: a transcription factor involved in the pathogenesis of myeloid and lymphoid leukemias.AML1基因:一种参与髓系和淋巴系白血病发病机制的转录因子。
Haematologica. 1997 May-Jun;82(3):364-70.
4
Persistence of multipotent progenitors expressing AML1/ETO transcripts in long-term remission patients with t(8;21) acute myelogenous leukemia.在伴有t(8;21)急性髓性白血病的长期缓解患者中,表达AML1/ETO转录本的多能祖细胞的持续性。
Blood. 1996 Jun 1;87(11):4789-96.
5
Identical fusion transcript associated with different breakpoints in the AML1 gene in simple and variant t(8;21) acute myeloid leukemia.与单纯型和变异型t(8;21)急性髓系白血病中AML1基因不同断点相关的相同融合转录本
Leukemia. 1995 Feb;9(2):282-7.
6
ETO and AML1 phosphoproteins are expressed in CD34+ hematopoietic progenitors: implications for t(8;21) leukemogenesis and monitoring residual disease.ETO和AML1磷酸化蛋白在CD34+造血祖细胞中表达:对t(8;21)白血病发生及残留疾病监测的意义。
Blood. 1996 Sep 1;88(5):1813-23.
7
Rearrangement of the AML1/CBFA2 gene in myeloid leukemia with the 3;21 translocation: expression of co-existing multiple chimeric genes with similar functions as transcriptional repressors, but with opposite tumorigenic properties.伴有3;21易位的髓系白血病中AML1/CBFA2基因重排:共存的多个嵌合基因的表达,这些基因作为转录抑制因子具有相似功能,但具有相反的致瘤特性。
Curr Top Microbiol Immunol. 1996;211:243-52. doi: 10.1007/978-3-642-85232-9_24.
8
[Study of genes involved in chronic myeloid leukemia with t (3; 21) (q26; q22) in blastic crisis].[伴t(3;21)(q26;q22)的慢性髓性白血病急变期相关基因的研究]
Zhonghua Xue Ye Xue Za Zhi. 2006 May;27(5):310-3.
9
The chimeric genes AML1/MDS1 and AML1/EAP inhibit AML1B activation at the CSF1R promoter, but only AML1/MDS1 has tumor-promoter properties.嵌合基因AML1/MDS1和AML1/EAP在集落刺激因子1受体(CSF1R)启动子处抑制AML1B的激活,但只有AML1/MDS1具有肿瘤促进特性。
Proc Natl Acad Sci U S A. 1996 Feb 6;93(3):1044-8. doi: 10.1073/pnas.93.3.1044.
10
t(3;21)(q26;q22) in myeloid leukemia: an aggressive syndrome of blast transformation associated with hydroxyurea or antimetabolite therapy.髓系白血病中的t(3;21)(q26;q22):一种与羟基脲或抗代谢物治疗相关的侵袭性原始细胞转化综合征。
Cancer. 2006 Apr 15;106(8):1730-8. doi: 10.1002/cncr.21797.

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Int J Mol Sci. 2019 Dec 5;20(24):6141. doi: 10.3390/ijms20246141.
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Heliyon. 2019 Jun 19;5(6):e01951. doi: 10.1016/j.heliyon.2019.e01951. eCollection 2019 Jun.
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Genome-wide haplotype association study identify the FGFR2 gene as a risk gene for acute myeloid leukemia.全基因组单倍型关联研究确定FGFR2基因为急性髓系白血病的风险基因。
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