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[颈动脉手术在预防脑梗死中的作用]

[Role of carotid surgery in the prevention of cerebral infarction].

作者信息

Limet R, Desiron Q, Detry O, Creemers E, Van Damme H

机构信息

Service de Chirurgie cardio-vasculaire, CHU du Sart Tilman de l'Université de Liège.

出版信息

Bull Mem Acad R Med Belg. 1994;149(5-7):299-305; discussion 306-7.

PMID:7795552
Abstract

A significant part of transient or permanent cerebral ischemic attacks (CIA) are due to arterio-arterial emboli issued from carotid plaques. Surgery for carotid disobstruction aims to take out emboligenic plaques by endarterectomy (associated to angioplasty or not). The adversaries of surgical treatment sustain two main assertions: 1. carotid stenoses are not very dangerous, because the definitive thromboses they create are easily compensated by the development of collaterals, so that the risk for stroke is low. 2. this low and late risk of spontaneous carotid thrombosis is not greater than the immediate one following carotid surgery. Those objections have been encountered in randomized North American studies (Nascet & Veterans) that have been published in 1991 and 1993. They show the usefulness of correctly done surgical correction as well as for symptomatic as asymptomatic stenoses. So do we it, presenting the results of our series (2.282 procedures in 1.868 patients). The results of our series show a low combined morbidity-mortality rate (1.7%), and a yearly stroke of 1.4%.

摘要

短暂性或永久性脑缺血发作(CIA)的一个重要部分是由于颈动脉斑块产生的动脉-动脉栓塞。颈动脉疏通手术旨在通过内膜切除术(无论是否联合血管成形术)切除产生栓子的斑块。手术治疗的反对者主要有两个观点:1. 颈动脉狭窄不太危险,因为其形成的最终血栓很容易通过侧支循环的发展得到代偿,所以中风风险较低。2. 颈动脉自发血栓形成的这种低风险且较晚出现的风险并不高于颈动脉手术后立即出现的风险。这些反对意见在1991年和1993年发表的北美随机研究(Nascet和退伍军人研究)中就已出现。这些研究表明,正确进行的手术矫正对于有症状和无症状狭窄都是有用的。我们也是如此,展示了我们系列研究的结果(1868例患者的2282例手术)。我们系列研究的结果显示,综合发病率和死亡率较低(1.7%),每年中风率为1.4%。

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