Orlando J, Aronow W S, Cassidy J, Prakash P
Ann Intern Med. 1976 Jun;84(6):652-5. doi: 10.7326/0003-4819-84-6-652.
We evaluated the effect of ethanol on exercise performance until angina in 12 patients in a double-blind, randomized study. The mean resting heart rate times systolic blood pressure was not changed after Fresca but was increased after 2 ounces of ethanol (P less than 0.001) and after 5 ounces of ethanol (P less than 0.01). Compared to the control periods, the mean exercise time until angina was not different after Fresca but was decreased after 2 ounces of ethanol (P less than 0.001) and after 5 ounces of ethanol (P less than 0.001). Compared to the control periods, the mean maximal ischemic ST-segment depression after angina was not changed after Fresca but was increased after 2 ounces of ethanol (P less than 0.01) and after 5 ounces of ethanol (P less than 0.001). Drinking 5 ounces or 2 ounces of ethanol decreases exercise duration until angina and increases ischemic ST-segment depression after angina.
在一项双盲、随机研究中，我们评估了乙醇对12例患者运动至心绞痛时运动表现的影响。饮用 Fresca 后静息心率与收缩压的乘积未发生变化，但饮用2盎司乙醇后（P<0.001）以及饮用5盎司乙醇后（P<0.01）该乘积增加。与对照期相比，饮用 Fresca 后运动至心绞痛的平均时间无差异，但饮用2盎司乙醇后（P<0.001）以及饮用5盎司乙醇后（P<0.001）该时间缩短。与对照期相比，饮用 Fresca 后心绞痛发作后的平均最大缺血性ST段压低未发生变化，但饮用2盎司乙醇后（P<0.01）以及饮用5盎司乙醇后（P<0.001）该压低增加。饮用5盎司或2盎司乙醇会缩短运动至心绞痛的持续时间，并增加心绞痛发作后的缺血性ST段压低。
