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Role of glial-derived nexin in neuronal differentiation and in acute brain injury and potential involvement in exacerbation of neurodegeneration in Alzheimer's disease.

作者信息

Shea T B

机构信息

Laboratories for Molecular Neuroscience, Mailman Research Center, McLean Hospital, Belmont, MA 02178, USA.

出版信息

Brain Res Brain Res Rev. 1995 Feb;20(2):171-84. doi: 10.1016/0165-0173(94)00010-m.

DOI:10.1016/0165-0173(94)00010-m
PMID:7795655
Abstract
摘要

相似文献

1
Role of glial-derived nexin in neuronal differentiation and in acute brain injury and potential involvement in exacerbation of neurodegeneration in Alzheimer's disease.神经胶质衍生的神经蛋白酶在神经元分化、急性脑损伤中的作用以及在阿尔茨海默病神经退行性变加重过程中的潜在参与情况。
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Regulation of neurons and astrocytes by thrombin and protease nexin-1. Relationship to brain injury.
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Prevention of activity-dependent neuronal death: vasoactive intestinal polypeptide stimulates astrocytes to secrete the thrombin-inhibiting neurotrophic serpin, protease nexin I.预防活动依赖性神经元死亡:血管活性肠肽刺激星形胶质细胞分泌凝血酶抑制性神经营养丝氨酸蛋白酶抑制剂——蛋白酶连接素I。
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Decreases in protease nexins in Alzheimer's disease brain.阿尔茨海默病大脑中蛋白酶连接素的减少。
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Regulation of neuronal cells and astrocytes by protease nexin-1 and thrombin.
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Protease nexin-1, a potent thrombin inhibitor, is reduced around cerebral blood vessels in Alzheimer's disease.蛋白酶连接素-1是一种有效的凝血酶抑制剂,在阿尔茨海默病患者的脑血管周围含量降低。
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Relevance of the balance between glia-derived nexin and thrombin following lesion in the nervous system.神经系统损伤后胶质细胞衍生的神经毒素与凝血酶之间平衡的相关性。
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引用本文的文献

1
While I Still Remember: 30 Years of Alzheimer's Disease Research.《当我还记得时:阿尔茨海默病研究 30 年》
J Alzheimers Dis. 2018;62(3):1049-1057. doi: 10.3233/JAD-170724.
2
Protease nexin I (PNI) in mouse brain is expressed from the same gene as in seminal vesicle.小鼠脑中的蛋白酶nexin I(PNI)与精囊中的蛋白酶nexin I由同一基因表达。
J Mol Neurosci. 1996 Fall;7(3):183-91. doi: 10.1007/BF02736839.