Corda M
Ann Sclavo. 1975 May-Jun;17(3):354-84.
Some ascertained the utility of the quantitative bacteriology in pneumology especially for the diagnosis of acute bronchopulmonary infections. Miles and Mizra technique lightly changed as analytically here described is suitable for counts of viable bacteria in sputum after liquefaction by N-acetyl-l-cisteine. Some researches prove that the technique is convenient for the control of chronic bronchopulmonary infections too with some restrictions. Quantitative tests are important to ascertain aetiological function of the bacteria in sputum and in bronchial secretions. Particularly 10(7)-10(9) coliforms per ml of sputum are likely pathogenic. The observation of the early quantitative changes of bacteria in sputum during antibiotic treatments is suitable for in vivo tests of microbial sensitivity to drugs and is preferable to the usual in vitro antibiograms.
一些人确定了定量细菌学在肺病学中的实用性，特别是在急性支气管肺部感染的诊断方面。迈尔斯和米兹拉技术（在此处分析时略有改动）适用于通过N-乙酰-L-半胱氨酸液化后痰液中活菌的计数。一些研究证明，该技术在有一些限制的情况下，对慢性支气管肺部感染的控制也很方便。定量检测对于确定痰液和支气管分泌物中细菌的病因学作用很重要。特别是每毫升痰液中有10⁷ - 10⁹个大肠菌群可能具有致病性。观察抗生素治疗期间痰液中细菌的早期定量变化适用于微生物对药物敏感性的体内测试，并且比通常的体外药敏试验更可取。
