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加纳北部儿童死亡率的风险因素:一项病例对照研究。

Risk factors for child mortality in northern Ghana: a case-control study.

作者信息

Binka F N, Maude G H, Gyapong M, Ross D A, Smith P G

机构信息

Navrongo Health Research Centre, Ministry of Health, Ghana.

出版信息

Int J Epidemiol. 1995 Feb;24(1):127-35. doi: 10.1093/ije/24.1.127.

Abstract

BACKGROUND

A population-based case-control study was carried out to investigate potential risk factors for post-neonatal and child mortality in northern Ghana were child survival rates are among the lowest in Africa.

METHOD

Cases were post-neonatal infant and child deaths identified within a large population under continuous demographic surveillance. For each case, one living control, matched for age, sex and locality, was selected from the demographic database. Mothers of each case and control were interviewed to obtain information on social, enconomic, demographic, environmental and other possible risk factors. Matched analyses of the 317 cases and their controls were performed using discordant pairs analysis and conditional logistic regression.

RESULTS

The mortality rate for children aged 6 months to 4 years was estimated as 23.9/1000 children/year. An increased risk of death was observed where the delivery was not performed by a trained person (OR = 1.8, 95% CI: 1.0-3.2), if the preceding birth interval was < 24 months (OR = 2.2, 95% CI: 1.1-3.9), if the father beat the child's mother (OR = 4.3, 95% CI: 1.2-15.6) or if the water source was unprotected (OR = 1.6, 95% CI: 1.0-2.7). No association was found between weaning practices, parental education, or any of the socioeconomic or hygiene variables considered.

CONCLUSIONS

Few strong risk factors for mortality were identified, perhaps because living conditions within the study population are relatively homogeneous. While mortality rates may be reduced by targeted interventions, such as increasing deliveries by trained people, more general improvements in the socioeconomic status in the region are essential.

摘要

背景

在加纳北部开展了一项基于人群的病例对照研究,以调查新生儿后期和儿童死亡的潜在风险因素,该地区的儿童存活率在非洲是最低的。

方法

病例为在持续人口监测的大量人群中确定的新生儿后期婴儿和儿童死亡。对于每个病例,从人口数据库中选择一名年龄、性别和地点匹配的存活对照。对每个病例和对照的母亲进行访谈,以获取有关社会、经济、人口、环境和其他可能风险因素的信息。使用不一致对分析和条件逻辑回归对317例病例及其对照进行匹配分析。

结果

估计6个月至4岁儿童的死亡率为23.9/1000儿童/年。观察到,如果分娩不是由经过培训的人员进行(比值比=1.8,95%可信区间:1.0-3.2),如果前次生育间隔<24个月(比值比=2.2,95%可信区间:1.1-3.9),如果父亲殴打孩子的母亲(比值比=4.3,95%可信区间:1.2-15.6),或者如果水源未受保护(比值比=1.6,95%可信区间:1.0-2.7),则死亡风险增加。在断奶方式、父母教育程度或所考虑的任何社会经济或卫生变量之间未发现关联。

结论

确定的死亡风险因素较少,可能是因为研究人群中的生活条件相对同质。虽然通过有针对性的干预措施,如增加由经过培训的人员接生,可以降低死亡率,但该地区社会经济状况的更普遍改善至关重要。

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