Gilmore R
Department of Neurology, University of Florida Health Science Center, Gainesville 32610, USA.
J Clin Neurophysiol. 1995 Mar;12(2):132-8. doi: 10.1097/00004691-199503000-00003.
Evoked potentials (EPs) provide a quantitative measure of function rather than structure of certain pathways and processes within the nervous system. These systems and processes change with maturation and senescence. There are minimal somatosensory EPs changes after maturation until senescence. There are moderate changes in interpeak latencies, but few changes in the central conduction time (CCT). Brainstem auditory EPs change minimally with aging, with the CCT prolonging by 1-4 ms/year, possibly in a gender-dependent fashion. Latencies of visual EPs prolong by 2-4 ms/decade after age 40 years. The P300 amplitude, latency, and distribution all change with age. An understanding of the characteristics of EPs in aging humans is essential to accurate clinical interpretation of these studies.
诱发电位（EPs）提供了一种对神经系统内特定通路和过程的功能而非结构的定量测量方法。这些系统和过程会随着成熟和衰老而发生变化。成熟后到衰老前，体感诱发电位的变化极小。峰间潜伏期有适度变化，但中枢传导时间（CCT）变化很少。脑干听觉诱发电位随年龄增长变化极小，CCT每年延长1 - 4毫秒，可能存在性别差异。40岁以后，视觉诱发电位的潜伏期每十年延长2 - 4毫秒。P300的波幅、潜伏期和分布都会随年龄变化。了解老年人诱发电位的特征对于准确临床解读这些研究至关重要。
