大肠杆菌的TyrR蛋白是一种I类转录激活因子。
The TyrR protein of Escherichia coli is a class I transcription activator.
作者信息
Lawley B, Fujita N, Ishihama A, Pittard A J
机构信息
Department of Microbiology, University of Melbourne, Parkville, Victoria, Australia.
出版信息
J Bacteriol. 1995 Jan;177(1):238-41. doi: 10.1128/jb.177.1.238-241.1995.
Abstract
The purified TyrR protein and phenylalanine were sufficient to activate in vitro transcription from the tyrP promoter by wild-type RNA polymerase. Such TyrR-mediated activation did not occur when the mutant alpha 235 RNA polymerase was used, indicating that TyrR is a class I transcription activator.
摘要
纯化的TyrR蛋白和苯丙氨酸足以通过野生型RNA聚合酶激活来自tyrP启动子的体外转录。当使用突变的α235 RNA聚合酶时，这种TyrR介导的激活不会发生，这表明TyrR是I类转录激活因子。
相似文献
1
The TyrR protein of Escherichia coli is a class I transcription activator.大肠杆菌的TyrR蛋白是一种I类转录激活因子。
J Bacteriol. 1995 Jan;177(1):238-41. doi: 10.1128/jb.177.1.238-241.1995.
2
Mode of action of the TyrR protein: repression and activation of the tyrP promoter of Escherichia coli.TyrR蛋白的作用模式：大肠杆菌tyrP启动子的阻遏与激活
Mol Microbiol. 2004 Apr;52(1):243-56. doi: 10.1111/j.1365-2958.2003.03965.x.
3
Demonstration that the TyrR protein and RNA polymerase complex formed at the divergent P3 promoter inhibits binding of RNA polymerase to the major promoter, P1, of the aroP gene of Escherichia coli.证明在发散型P3启动子处形成的TyrR蛋白与RNA聚合酶复合物会抑制RNA聚合酶与大肠杆菌aroP基因的主要启动子P1的结合。
J Bacteriol. 1998 Oct;180(20):5466-72. doi: 10.1128/JB.180.20.5466-5472.1998.
4
Amino acid residues in the alpha-subunit C-terminal domain of Escherichia coli RNA polymerase involved in activation of transcription from the mtr promoter.大肠杆菌RNA聚合酶α亚基C末端结构域中参与mtr启动子转录激活的氨基酸残基。
J Bacteriol. 1997 Oct;179(19):6187-91. doi: 10.1128/jb.179.19.6187-6191.1997.
5
Critical base pairs and amino acid residues for protein-DNA interaction between the TyrR protein and tyrP operator of Escherichia coli.大肠杆菌TyrR蛋白与tyrP操纵基因之间蛋白质-DNA相互作用的关键碱基对和氨基酸残基
J Bacteriol. 1997 Feb;179(4):1051-8. doi: 10.1128/jb.179.4.1051-1058.1997.
6
In vitro transcriptional analysis of TyrR-mediated activation of the mtr and tyrP+3 promoters of Escherichia coli.大肠杆菌中TyrR介导的mtr和tyrP +3启动子激活的体外转录分析。
J Bacteriol. 1996 Nov;178(21):6389-93. doi: 10.1128/jb.178.21.6389-6393.1996.
7
The various strategies within the TyrR regulation of Escherichia coli to modulate gene expression.大肠杆菌中TyrR调控内用于调节基因表达的各种策略。
Genes Cells. 1996 Aug;1(8):717-25. doi: 10.1111/j.1365-2443.1996.tb00012.x.
8
Analysis of an Escherichia coli mutant TyrR protein with impaired capacity for tyrosine-mediated repression, but still able to activate at sigma 70 promoters.对一种大肠杆菌突变型TyrR蛋白的分析，该蛋白酪氨酸介导的阻遏能力受损，但仍能在σ70启动子处激活。
Mol Microbiol. 1995 Aug;17(3):471-81. doi: 10.1111/j.1365-2958.1995.mmi_17030471.x.
9
Specific contacts between residues in the DNA-binding domain of the TyrR protein and bases in the operator of the tyrP gene of Escherichia coli.大肠杆菌TyrR蛋白DNA结合结构域中的残基与tyrP基因操纵子中的碱基之间的特异性接触。
J Bacteriol. 1999 Apr;181(8):2338-45. doi: 10.1128/JB.181.8.2338-2345.1999.
10
Mechanism of repression of the aroP P2 promoter by the TyrR protein of Escherichia coli.大肠杆菌TyrR蛋白对aroP P2启动子的抑制机制。
J Bacteriol. 1999 Oct;181(20):6411-8. doi: 10.1128/JB.181.20.6411-6418.1999.
引用本文的文献
1
Activation by TyrR in Escherichia coli K-12 by Interaction between TyrR and the α-Subunit of RNA Polymerase.在大肠杆菌 K-12 中，TyrR 通过与 RNA 聚合酶α 亚基相互作用而被激活。
J Bacteriol. 2021 Sep 8;203(19):e0025221. doi: 10.1128/JB.00252-21.
2
Characterization of the TyrR Regulon in the Rhizobacterium Enterobacter ludwigii UW5 Reveals Overlap with the CpxR Envelope Stress Response.根际细菌恶臭假单胞菌 UW5 中 TyrR 调控基因的特性研究表明其与 CpxR 包膜应激反应有重叠。
J Bacteriol. 2020 Dec 7;203(1). doi: 10.1128/JB.00313-20.
3
The Uropathogenic Specific Protein Gene from and is a Novel Member of the TyrR and H-NS Regulons.来自[具体来源未给出]的尿路致病性特异性蛋白基因是TyrR和H-NS调控子的一个新成员。
Microorganisms. 2020 Feb 26;8(3):330. doi: 10.3390/microorganisms8030330.
4
The TyrR transcription factor regulates the divergent akr-ipdC operons of Enterobacter cloacae UW5.TyrR转录因子调控阴沟肠杆菌UW5的双向akr-ipdC操纵子。
PLoS One. 2015 Mar 26;10(3):e0121241. doi: 10.1371/journal.pone.0121241. eCollection 2015.
5
Altered oligomerization properties of N316 mutants of Escherichia coli TyrR.大肠杆菌TyrR的N316突变体的寡聚化特性改变
J Bacteriol. 2008 Dec;190(24):8238-43. doi: 10.1128/JB.00889-08. Epub 2008 Oct 17.
6
Reconstitution of acetosyringone-mediated Agrobacterium tumefaciens virulence gene expression in the heterologous host Escherichia coli.乙酰丁香酮介导的根癌农杆菌毒性基因在异源宿主大肠杆菌中的表达重构
J Bacteriol. 2001 Jun;183(12):3704-11. doi: 10.1128/JB.183.12.3704-3711.2001.
7
RegulonDB (version 3.2): transcriptional regulation and operon organization in Escherichia coli K-12.调控基因数据库（版本3.2）：大肠杆菌K-12中的转录调控与操纵子结构
Nucleic Acids Res. 2001 Jan 1;29(1):72-4. doi: 10.1093/nar/29.1.72.
8
Cloning and random mutagenesis of the Erwinia herbicola tyrR gene for high-level expression of tyrosine phenol-lyase.用于酪氨酸酚裂解酶高水平表达的草生欧文氏菌tyrR基因的克隆与随机诱变
Appl Environ Microbiol. 2000 Nov;66(11):4764-71. doi: 10.1128/AEM.66.11.4764-4771.2000.
9
The sigma(70) transcription factor TyrR has zinc-stimulated phosphatase activity that is inhibited by ATP and tyrosine.σ（70）转录因子TyrR具有锌刺激的磷酸酶活性，该活性受到ATP和酪氨酸的抑制。
J Bacteriol. 2000 Feb;182(4):1053-61. doi: 10.1128/JB.182.4.1053-1061.2000.
10
Transcriptional activation of Agrobacterium tumefaciens virulence gene promoters in Escherichia coli requires the A. tumefaciens RpoA gene, encoding the alpha subunit of RNA polymerase.根癌土壤杆菌毒力基因启动子在大肠杆菌中的转录激活需要根癌土壤杆菌的RpoA基因，该基因编码RNA聚合酶的α亚基。
J Bacteriol. 1999 Aug;181(15):4533-9. doi: 10.1128/JB.181.15.4533-4539.1999.
本文引用的文献
1
Involvement of the RNA polymerase alpha subunit C-terminal region in co-operative interaction and transcriptional activation with OxyR protein.RNA聚合酶α亚基C末端区域参与与OxyR蛋白的协同相互作用和转录激活。
Mol Microbiol. 1993 Mar;7(6):859-64. doi: 10.1111/j.1365-2958.1993.tb01176.x.
2
Protein-protein communication within the transcription apparatus.转录装置内的蛋白质-蛋白质通讯。
J Bacteriol. 1993 May;175(9):2483-9. doi: 10.1128/jb.175.9.2483-2489.1993.
3
The Ada protein is a class I transcription factor of Escherichia coli.Ada蛋白是大肠杆菌的一种I类转录因子。
J Bacteriol. 1993 Apr;175(8):2455-7. doi: 10.1128/jb.175.8.2455-2457.1993.
4
A genetic analysis of various functions of the TyrR protein of Escherichia coli.大肠杆菌TyrR蛋白多种功能的遗传分析。
J Bacteriol. 1993 Mar;175(6):1767-76. doi: 10.1128/jb.175.6.1767-1776.1993.
5
Role of the sigma 70 subunit of RNA polymerase in transcriptional activation by activator protein PhoB in Escherichia coli.RNA聚合酶的σ70亚基在大肠杆菌中激活蛋白PhoB介导的转录激活中的作用。
Genes Dev. 1993 Jan;7(1):149-60. doi: 10.1101/gad.7.1.149.
6
Mutations in the tyrR gene of Escherichia coli which affect TyrR-mediated activation but not TyrR-mediated repression.大肠杆菌tyrR基因中的突变，这些突变影响TyrR介导的激活作用，但不影响TyrR介导的阻遏作用。
J Bacteriol. 1993 Oct;175(19):6372-5. doi: 10.1128/jb.175.19.6372-6375.1993.
7
E. coli RNA polymerase, deleted in the C-terminal part of its alpha-subunit, interacts differently with the cAMP-CRP complex at the lacP1 and at the galP1 promoter.在其α亚基的C末端部分缺失的大肠杆菌RNA聚合酶，在lacP1和galP1启动子处与cAMP-CRP复合物的相互作用不同。
Nucleic Acids Res. 1993 Jan 25;21(2):319-26. doi: 10.1093/nar/21.2.319.
8
Role of the sigma 70 subunit of Escherichia coli RNA polymerase in transcription activation.大肠杆菌RNA聚合酶的σ70亚基在转录激活中的作用。
J Mol Biol. 1994 Jan 14;235(2):405-13. doi: 10.1006/jmbi.1994.1001.
9
Target of the transcriptional activation function of phage lambda cI protein.噬菌体λ cI蛋白转录激活功能的靶标。
Science. 1994 Jan 7;263(5143):75-7. doi: 10.1126/science.8272867.
10
The C terminus of the alpha subunit of RNA polymerase is not essential for transcriptional activation of sigma 54 holoenzyme.RNA聚合酶α亚基的C末端对于σ54全酶的转录激活并非必不可少。
J Bacteriol. 1993 Apr;175(8):2479-82. doi: 10.1128/jb.175.8.2479-2482.1993.
Zotero 插件