Pintus S, Pintus P, Piras C, Loviselli A, Muntoni S
Dismetabolic Diseases Centre, St. Michele Hospital, Cagliari, Italy.
J Clin Apher. 1994;9(2):124-5. doi: 10.1002/jca.2920090206.
Removal of low-density lipoproteins from plasma by dextran sulfate adsorption (DSA) in FH patients entails a decrease in plasma levels of thyroid hormones (-28.5% and -18.7%, respectively, for T3 and T4). This suggests that FH patients have a greater than normal fraction of thyroid hormones bound to lipoproteins, due to their expanded lipoprotein pool.
通过硫酸葡聚糖吸附（DSA）从家族性高胆固醇血症（FH）患者血浆中去除低密度脂蛋白会导致甲状腺激素血浆水平降低（T3和T4分别降低28.5%和18.7%）。这表明，由于脂蛋白池扩大，FH患者与脂蛋白结合的甲状腺激素比例高于正常水平。
