Shane J M, Walker P M
Department of Family and Consumer Sciences, Illinois State University, Normal 61790.
J Am Diet Assoc. 1995 Jan;95(1):40-5. doi: 10.1016/S0002-8223(95)00011-9.
The purpose of this study was to determine the lipid-lowering effects of dietary corn bran fed in moderate supplemental doses to men with hypercholesterolemia consuming a low-fat diet.
The 98-day study was divided into one 2-week preperiod and two 6-week experimental periods in a cross-over design.
The study was conducted in the metabolic diet kitchen of the Department of Home Economics and the Nutrition Research Laboratory of the Department of Agriculture at Illinois State University, Normal.
Twenty-nine sedentary men with hypercholesterolemia, aged 38 to 70 years, participated in the project. All of them completed the study.
After a 2-week adjustment period in which subjects consumed a low-fat controlled diet, subjects were assigned to one of two experimental treatments: low-fat controlled diet plus 20 g corn bran supplement or low-fat controlled diet plus 20 g wheat bran supplement.
Lipid measurements included total cholesterol, low-density lipoprotein cholesterol (LDL-C), high-density lipoprotein cholesterol (HDL-C), very-low-density lipoprotein cholesterol (VLDL-C), and triglyceride concentrations.
Differences in lipid parameters were analyzed using two-way analysis of variance with repeated measures (P < .05). A paired t test was used to assess differences between treatment periods for each subject.
The low-fat controlled diet significantly lowered all serum parameters analyzed except HDL-C. Corn fiber supplementation resulted in an additional lowering of serum total cholesterol, triglyceride, and VLDL-C concentrations. Serum LDL-C and HDL-C concentrations were not significantly altered by corn fiber or wheat fiber supplementation.
This study suggests that supplementing a low-fat diet with corn bran is affective in reducing serum lipid concentrations for men with hypercholesterolemia.
本研究的目的是确定在低脂饮食的高胆固醇血症男性中，中等补充剂量的膳食玉米麸的降脂效果。
这项为期98天的研究采用交叉设计，分为一个2周的前期和两个6周的实验期。
该研究在伊利诺伊州立大学诺默尔分校家政系的代谢饮食厨房和农业系的营养研究实验室进行。
29名年龄在38至70岁之间的久坐不动的高胆固醇血症男性参与了该项目。他们全部完成了研究。
在为期2周的调整期内，受试者食用低脂控制饮食，之后将受试者分配到两种实验处理之一：低脂控制饮食加20克玉米麸补充剂或低脂控制饮食加20克麦麸补充剂。
血脂测量包括总胆固醇、低密度脂蛋白胆固醇（LDL-C）、高密度脂蛋白胆固醇（HDL-C）、极低密度脂蛋白胆固醇（VLDL-C）和甘油三酯浓度。
使用重复测量的双向方差分析（P < .05）分析血脂参数的差异。采用配对t检验评估每个受试者不同治疗期之间的差异。
低脂控制饮食显著降低了除HDL-C之外的所有分析血清参数。补充玉米纤维导致血清总胆固醇、甘油三酯和VLDL-C浓度进一步降低。补充玉米纤维或麦麸对血清LDL-C和HDL-C浓度没有显著影响。
本研究表明，用玉米麸补充低脂饮食对降低高胆固醇血症男性的血清脂质浓度有效。
