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系统性红斑狼疮和霍奇金病中的抗淋巴细胞抗体:免疫荧光法比较

Anti-lymphocyte antibodies in systemic lupus erythematosus and in Hodgkin's disease: a comparison by immunofluorescence.

作者信息

Del Giacco G S, Leone A L, Locci F, Manconi P E, Tognella S, Mantovani G, Grifoni V

出版信息

Biomedicine. 1976 May;25(3):79-80.

PMID:779861
Abstract

Anti-lymphocyte antibodies of IgM type (cold reactive) in systemic lupus erythematosus and of IgG type (not cold reactive) in Hodgkin's disease have been demonstrated by immunofluorescence to attach the same target cell (T-lymphocyte.) The same behaviour of both kinds of antibodies in "co-capping" experiments confirm that the antigen on the cell surface is the same. Hypothesis about the meaning of this phenomenon are made.

摘要

通过免疫荧光法已证实,系统性红斑狼疮中IgM型(冷反应性)抗淋巴细胞抗体以及霍奇金病中IgG型(非冷反应性)抗淋巴细胞抗体可附着于同一靶细胞(T淋巴细胞)。在“共帽”实验中这两种抗体的相同行为证实细胞表面的抗原是相同的。文中对这一现象的意义提出了假设。

相似文献

1
Anti-lymphocyte antibodies in systemic lupus erythematosus and in Hodgkin's disease: a comparison by immunofluorescence.系统性红斑狼疮和霍奇金病中的抗淋巴细胞抗体:免疫荧光法比较
Biomedicine. 1976 May;25(3):79-80.
2
[Comparison between anti-lymphocyte antibodies in systemic lupus erythematosus and in Hodgkin's disease].[系统性红斑狼疮与霍奇金病中抗淋巴细胞抗体的比较]
Boll Ist Sieroter Milan. 1976 Jul 31;55(3):255-61.
3
Modulation of IgM anti-lymphocyte antibody-reactive T cell surface antigens in systemic lupus erythematosus.系统性红斑狼疮中IgM抗淋巴细胞抗体反应性T细胞表面抗原的调节
J Immunol. 1986 May 1;136(9):3246-53.
4
Studies on antilymphocyte antibodies in patients with rheumatoid arthritis and systemic lupus erythematosus.类风湿性关节炎和系统性红斑狼疮患者抗淋巴细胞抗体的研究。
Rheumatology. 1975;6:209-14.
5
Anti-lymphocyte antibodies in systemic lupus erythematosus.系统性红斑狼疮中的抗淋巴细胞抗体。
Clin Rheum Dis. 1985 Dec;11(3):523-49.
6
Identification of three major target molecules of IgM antilymphocyte autoantibodies in systemic lupus erythematosus.系统性红斑狼疮中IgM抗淋巴细胞自身抗体的三种主要靶分子的鉴定。
J Immunol. 1987 Dec 1;139(11):3644-51.
7
Analyses of lymphocytes from patients with rheumatoid arthritis and systemic lupus erythematosus. Occurrence of interfering cold-reactive antilymphocyte antibodies.类风湿性关节炎和系统性红斑狼疮患者淋巴细胞分析。干扰性冷反应性抗淋巴细胞抗体的出现。
J Clin Invest. 1974 Nov;54(5):1082-92. doi: 10.1172/JCI107852.
8
Cell-surface modifications of normal human peripheral lymphocytes induced by lymphocytotoxic sera of patients with systemic lupus erythematosus and Hodgkin's disease, studied by scanning electron microscopy.通过扫描电子显微镜研究系统性红斑狼疮和霍奇金病患者的淋巴细胞毒性血清诱导的正常人外周淋巴细胞的细胞表面修饰。
Haematologica. 1979 Apr;64(2):148-58.
9
Characterization of warm-reactive IgG anti-lymphocyte antibodies in systemic lupus erythematosus. Relative specificity for mitogen-activated T cells and their soluble products.系统性红斑狼疮中温热反应性IgG抗淋巴细胞抗体的特征。对丝裂原激活的T细胞及其可溶性产物的相对特异性。
J Immunol. 1983 Jan;130(1):181-6.
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IgG anti-lymphocyte antibodies in systemic lupus erythematosus react with surface molecules shared by peripheral T cells and a primitive T cell line.系统性红斑狼疮中的IgG抗淋巴细胞抗体与外周T细胞和原始T细胞系共有的表面分子发生反应。
J Immunol. 1987 Mar 15;138(6):1750-6.

引用本文的文献

1
Anti-Ia reactivity in sera from patients with systemic lupus erythematosus.系统性红斑狼疮患者血清中的抗Ia反应性。
J Clin Invest. 1982 Jan;69(1):17-24. doi: 10.1172/jci110428.
2
Absence of IgG lymphocytotoxins in untreated Hodgkin's disease (HD) patients.未经治疗的霍奇金淋巴瘤(HD)患者中不存在IgG淋巴细胞毒素。
Clin Exp Immunol. 1978 Oct;34(1):100-5.