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肝病患者空腹与餐后血清总胆汁酸的对比研究:一项初步研究

Comparison study between fasting total serum bile acid and post prandial bile acid in hepatic diseases: a preliminary study.

作者信息

Boonyapisit S, Lekhakula S, Amornkittichareon B, Shumnumsirivath D

机构信息

Department of Medicine, Faculty of Medicine, Siriraj Hospital, Mahidol University, Bangkok, Thailand.

出版信息

J Med Assoc Thai. 1994 Jan;77(1):34-6.

PMID:7798828
Abstract

Fasting bile acid, two-hour post prandial bile acid and other liver function tests (Bili, AST, ALT, ALB, Glob, ALP) were measured in 22 normal and 28 liver diseased patients. In normal volunteers, the mean value of fasting total serum bile acid (FTBA) and postprandial serum bile acid (PTBA) were 3.08 mumole/L (S.D. 1.65) range 0.21-6.26 mumol/L, and 8.07 mumole/L (S.D. 2.99) range 4.06-15.65 mumole/L. Comparison between FTBA, PTBA and other liver function tests in various liver diseases from this study the PTBA was not statistically significant superior to FTBA. Therefore, it is not necessary to do the PTBA at this time until more data is available.

摘要

对22名正常人和28名肝病患者进行了空腹胆汁酸、餐后两小时胆汁酸及其他肝功能检查(胆红素、谷草转氨酶、谷丙转氨酶、白蛋白、球蛋白、碱性磷酸酶)。在正常志愿者中,空腹血清总胆汁酸(FTBA)和餐后血清胆汁酸(PTBA)的平均值分别为3.08微摩尔/升(标准差1.65,范围0.21 - 6.26微摩尔/升)和8.07微摩尔/升(标准差2.99,范围4.06 - 15.65微摩尔/升)。本研究对各种肝病中FTBA、PTBA及其他肝功能检查进行比较,结果显示PTBA在统计学上并不显著优于FTBA。因此,在获得更多数据之前,目前没有必要进行PTBA检查。

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